Results 241 to 250 of about 39,968 (294)

Intraoperative radiotherapy: The japanese experience

International Journal of Radiation Oncology Biology Physics, 1981
Abstract Clinical results of intraoperative radiotherapy ([OR) which have been obtained since 1964 in Japan were reviewed. In this radiotherapy a cancerocidal dose can be delivered safely to the lesions, since critical organs are shifted from the field so that the lesions may be exposed directly to radiation. Intraoperative radiotherapy has spread in
Masaji Takahashi
exaly   +3 more sources

Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial [PDF]

Lancet, The, 2010
Background: After breast-conserving surgery, 90% of local recurrences occur within the index quadrant despite the presence of multicentric cancers elsewhere in the breast.
Jayant S Vaidya, David J Joseph, Jeffrey S Tobias   +2 more
exaly   +3 more sources

Intraoperative radiotherapy for breast cancer: powerful evidence to change practice [PDF]

Nature Reviews Clinical Oncology, 2021
We believe that the recent News and Views article (Sasieni, P. D. & Sawyer, E. J. Intraoperative radiotherapy for early breast cancer — insufficient evidence to change practice. Nat. Rev. Clin. Oncol.
Max Bulsara, Michael Alvarado, Marcelle Bernstein   +2 more
exaly   +1 more source

An assessment of intraoperative radiotherapy

Health Policy, 1996
An assessment of intraoperative radiotherapy (IORT) was undertaken to inform a decision on whether this technology should be introduced into the state of New South Wales. On the basis of a literature review, IORT appeared to be essentially an experimental technology, with limited data to demonstrate its comparative advantage over other treatments ...
C, Patterson, D, Hailey
openaire   +2 more sources

Intraoperative radiotherapy for gliomas

Journal of Neuro-Oncology, 1995
Intraoperative radiotherapy (IORT) was performed in 20 of 36 patients with glioma; 11 glioblastomas, 7 malignant astrocytomas, 2 benign astrocytomas. Twenty or 25 Gy of irradiation was delivered in a single fraction intraoperatively, followed by external beam irradiation. The electron beam energy was selected so that the 80% isodose line fell at 2 or 3
T, Fujiwara, Y, Honma, T, Ogawa, K, Irie, H, Kuyama, S, Nagao, H, Takashima, A, Hosokawa, M, Ohkawa, M, Tanabe   +9 more
openaire   +2 more sources

Intraoperative radiotherapy

Radiotherapy and Oncology, 1986
The potential benefit of intraoperative radiotherapy (IORT) was originally recognized years ago and has recently attracted renewed interest. Modern radiotherapeutic approaches may be more successful as a result of technical innovation, particularly in the use of electron beam accelerators.
openaire   +2 more sources

[Intraoperative radiotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy, 1987
Intraoperative radiotherapy, which delivers a large single dose of electrons to a tumor intraoperatively, is applied for locally advanced and/or difficult to cure malignancies which are rather difficult to treat by conventional external beams. Although this method was initially developed in Japan, increasing numbers of institutes have recently been ...
K, Hata, M, Miyoshi, S, Uehara, Y, Shimamura, M, Furusawa, H, Tomoda, Y, Seo, M, Abe, Y, Hara, S, Jimi   +9 more
  +6 more sources

Intraoperative radiotherapy: current thinking

European Journal of Surgical Oncology (EJSO), 2002
Intraoperative radiotherapy (IORT) refers to the delivery of irradiation at surgery. A large single dose of irradiation is delivered to a surgically defined area, while uninvolved and dose-limiting tissues are displaced, the final goal of IORT being enhanced locoregional tumour control.
Valentini V, Balducci M, Tortoreto F, Morganti AG, De Giorgi U, Fiorentini G.   +5 more
openaire   +3 more sources

Intraoperative radiotherapy for pancreatic adenocarcinoma

Journal of Hepato-Biliary-Pancreatic Surgery, 1998
Intraoperative radiotherapy (IORT) is an innovative treatment approach for cancer of the pancreas. The common causes of treatment failure in pancreatic cancer are regional recurrence and distant metastasis. While at present the benefit of IORT in unresectable pancreatic cancer is still controversial and awaits further prospective trials for its ...
M, Sunamura, M, Kobari, L, Lozonschi, S, Egawa, S, Matsuno   +4 more
openaire   +2 more sources

Intraoperative radiotherapy for breast cancer

The Lancet Oncology, 2004
Postoperative radiotherapy, which forms part of breast-conserving therapy, may not need to encompass the whole breast. Apart from the consumption of huge resources and patients' time, postoperative radiotherapy deters many women from receiving the benefits of breast-conserving surgery, forcing them to choose a mastectomy instead.
Jayant S, Vaidya, Jeffrey S, Tobias, Michael, Baum, Mohammed, Keshtgar, David, Joseph, Frederik, Wenz, Joan, Houghton, Christobel, Saunders, Tammy, Corica, Derek, D'Souza, Richard, Sainsbury, Samuele, Massarut, Irving, Taylor, Basil, Hilaris   +13 more
openaire   +2 more sources