Results 131 to 140 of about 102,703 (336)

A proposal of Brazilian Society of Surgical Oncology for standardizing cytoreductive surgery plus hypertermic intraperitoneal chemotherapy procedures in Brazil: pseudomixoma peritonei, appendiceal tumors and malignant peritoneal mesothelioma

Revista do Colégio Brasileiro de Cirurgiões
Cytoreductive surgery plus hypertermic intraperitoneal chemotherapy has emerged as a major comprehensive treatment of peritoneal malignancies and is currently the standard of care for appendiceal epithelial neoplasms and pseudomyxoma peritonei syndrome ...
Thales Paulo Batista, Bruno José Queiroz Sarmento, Janina Ferreira Loureiro, Andrea Petruzziello, Ademar Lopes, Cassio Cortez Santos, Cláudio de Almeida Quadros, Eduardo Hiroshi Akaishi, Eduardo Zanella Cordeiro, Felipe José Fernández Coimbra, Gustavo Andreazza Laporte, Leonaldson Santos Castro, Ranyell Matheus Spencer Sobreira Batista, Samuel Aguiar Júnior, Wilson Luiz Costa Júnior, Fábio Oliveira Ferreira   +15 more
doaj   +1 more source

Peritonectomy and hyperthermic intraperitoneal chemotherapy for advanced epithelial ovarian cancer: What gynaecological oncologists really think [PDF]

, 2019
Rhonda Farrell
openalex   +1 more source

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

Post-operative weight loss affects 3-year survival in patients with gastric adenocarcinoma after gastrectomy and hyperthermic intraperitoneal chemotherapy

, 2023
Paméla Funk-Debleds, Julien Rossi, Lorraine Bernard, Alexandre Galan, Vahan Képénékian, Olivier Gléhen, C. Chambrier   +6 more
openalex   +2 more sources

Intraperitoneal chemotherapy for ovarian cancer with peritoneal metastases, systematic review of the literature and focused personal experience [PDF]

, 2021
Federico Coccolini, Paola Fugazzola, Giulia Montori, Luca Ansaloni, Massimo Chiarugi   +4 more
openalex   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

Injectable diblock copolypeptide hydrogel provides platform to maintain high local concentrations of taxol and local tumor control [PDF]

, 2019
Introduction Surgical resection and systemic chemotherapy with temozolomide remain the mainstay for treatment of glioblastoma. However, many patients are not candidates for surgical resection given inaccessible tumor location or poor health status ...
Bernstein, Alexander, Deming, Timothy, Garrett, Matthew, Hung, Derek, Kornblum, Harley, O’Shea, Timothy, Sofroniew, Michael, Soto, Horacio, Staarman, Brittany, Wollenberg, Alexander   +9 more
core  

Simultaneous Surgical Approach with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients with Concurrent Peritoneal and Liver Metastases of Colon Cancer Origin [PDF]

, 2023
Rafael Morales-Soriano, Cristina Pineño‐Flores, José Miguel Morón Canís, Francisco Javier Molina-Romero, José Carlos Rodríguez-Pino, Julia Loyola-Miró, Xavier González-Argenté, Elías Palma-Zamora, Mónica Guillot-Morales, Sandra Giménez, Melchor Álvarez‐Mon, Miguel Á. Ortega, Juan José Segura‐Sampedro   +12 more
openalex   +1 more source

WDR5‐H3K4me3 Epigenetic Axis Promotes TRMT6‐Dependent tRNA M1A Modification to Facilitate Triple‐Negative Breast Cancer Progression by Suppressing Ferroptosis

Advanced Science, EarlyView.
Upregulated TRMT6 forms aberrant hypermethylation of a specific tRNA pool and serves as a predictor of poor prognosis in TNBC. This m1A modification in tRNAs enhances translation of FTH1 and FTL, reducing the pool of bioavailable Fe2⁺. Reduced Fe2+ availability impairs RSL3‐induced lipid peroxidation and tumor progression.
Yuqing Lei, Xue Wang, Jiahe Liu, Zixu Niu, Jiaqi Hua, Qian Guo, Dan Du, Yuanchang Zhu, Fucheng He, Mingxia Zhou, Hongle Li, Jing He, Jun Li   +12 more
wiley   +1 more source

Low Preoperative Serum Albumin Levels Are Associated With Impaired Outcome After Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy for Peritoneal Surface Malignancies

, 2020
Charalampos Seretis, Jagjit S. Gill, Adnan Malik, Ali Mohamed Elhassan, Umar Shariff, Haney Youssef   +5 more
openalex   +2 more sources