Results 151 to 160 of about 1,075,882 (382)

Long‐term survival following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in Waikato, Aotearoa New Zealand: a 12‐year experience [PDF]

, 2023
Rennie Xinrui Qin, Jia Hui Lim, Jasen Ly, Jesse Fischer, Nicholas Smith, Mosese Karalus, Linus Wu, R. van Dalen, Simione Lolohea   +8 more
openalex   +1 more source

Proteogenomic Characterization Reveals Metabolic Vulnerabilities and Aberrant Phosphorylation in Colorectal Metastasis to Liver

Advanced Science, EarlyView.
This study provides a multi‐omics landscape of treatment‐naïve colorectal liver metastasis and reveals dysregulated molecules and cellular pathways. SHMT1 and NDRG1 Ser330 phosphorylation are demonstrated to display crucial roles in tumorigenesis and liver metastasis. Two proteomics subtypes (metabolism and RNA function) with distinct clinical outcomes
Wensi Zhao, Lei Zhao, Yannan Lian, Zhiwei Liu, Yaqi Li, Xuege Wang, Mingya Zhang, Ni Li, Jingli Guo, Danqing Shen, Shaobo Mo, Jiahao Li, Linhui Zhai, Jiahui Ni, Sangkyu Lee, Bin Liu, Jing Li, Fei Wang, Junjie Peng, Jun Qin, Minjia Tan   +20 more
wiley   +1 more source

Anti-Tumor Effects of TRAIL-Expressing Mesenchymal Stromal Cells in a Mouse Xenograft Model of Human Mesothelioma [PDF]

, 2015
Malignant mesothelioma (MM) remains a highly deadly malignancy with poor treatment option. The MM cells further promote a highly inflammatory microenvironment which contributes to tumor initiation, development, severity, and propagation. We reasoned that
Janes, SM, Sage, E
core  

Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) in colorectal cancer with peritoneal metastasis: Status quo and how should we proceed [PDF]

, 2020
Ingmar Königsrainer
openalex   +1 more source

Current Medical Care Situation of Patients in Germany Undergoing Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) [PDF]

, 2022
Philipp Horvath, Can Yurttas, Isabella D. Baur, Christoph Steidle, Marc A. Reymond, Paolo Girotti, Alfred Königsrainer, Ingmar Königsrainer   +7 more
openalex   +1 more source

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

Advanced Science, EarlyView.
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang, Kezhang He, Bowen Wang, Wei Zhou, Ying Zhang, Tianhua Ma, Sheng Ding   +6 more
wiley   +1 more source

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy – perioperative management at Waikato Hospital [PDF]

, 2019
Simon J. Davis, Kelly Byrne
openalex   +1 more source

Impact of Neoadjuvant Chemotherapy on the Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Colorectal Peritoneal Metastases: A Multi-Institutional Retrospective Review [PDF]

, 2020
Eliza W. Beal, Lorena P. Suarez‐Kelly, Charles W. Kimbrough, Fabian M. Johnston, Jonathan B. Greer, Daniel E. Abbott, Courtney Pokrzywa, Mustafa Raoof, Byrne Lee, Travis E. Grotz, Jennifer L. Leiting, Keith F. Fournier, Andrew Lee, Seán Dineen, Benjamin D. Powers, Jula Veerapong, Joel Baumgartner, Callisia N. Clarke, Harveshp Mogal, Marti C. Russell, M. Zaidi, Sameer H. Patel, Vikrom K. Dhar, Laura Lambert, Ryan J. Hendrix, John L. Hays, Sherif Abdel‐Misih, Jordan M. Cloyd   +27 more
openalex   +1 more source

Is there a role for hyperthermic intraperitoneal chemotherapy in ovarian cancer? [PDF]

, 2022
Aaron Praiss, Lea A. Moukarzel, Oliver Zivanovic   +2 more
openalex   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source