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Correction to "Implementation of a Multidisciplinary Enhanced Recovery After Surgery (ERAS) Program for Cytoreductive Surgery (CRS) With Hyperthermic Intraperitoneal Chemotherapy (HIPEC)". [PDF]

J Surg Oncol
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INTRAPERITONEAL CHEMOTHERAPY

Obstetrics and Gynecology Clinics of North America, 1994
Despite high initial tumor response rates to systemically administered platinum-based chemotherapy, fewer than one quarter of advanced-stage ovarian cancer patients currently experience prolonged disease-free survival. Because persistent and relapsed disease tends to remain confined to the peritoneal cavity, the strategy of enhancing drug delivery to ...
Michael F. Flessner, Robert L. Dedrick
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Intraperitoneal Chemotherapy with Melphalan

Annals of Internal Medicine, 1984
We administered melphalan by the intraperitoneal route to investigate its toxicity and pharmacokinetics. The drug was instilled with 2 litres of fluid and allowed to dwell in the peritoneal cavity for 4 hours. No local toxicity was detected by clinical examination, laboratory tests, or histologic examination.
S B, Howell, C E, Pfeifle, R A, Olshen
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Pharmacology of Intraperitoneal Chemotherapy

Cancer Investigation, 1983
In this review of the pharmacology and clinical application of intraperitoneal drug administration, we have tried to acquaint the reader with the current state of the art. At this juncture it is important to outline briefly some of the major remaining questions.
C E, Myers, J M, Collins
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Hyperthermic Intraperitoneal Chemotherapy

Advances in Anesthesia, 2005
Cancer treatment frequently requires a multimodality approach, involving surgical resection(s), radiotherapy, and chemotherapy. Advanced surgical approaches allow for the combination of two of these, offering patients intraoperative radiotherapy with surgical resection or intraoperative chemotherapy targeted and limited to a particular body region. The
Alicia M. Kowalski, Thomas B. Dougherty
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Intraperitoneal Chemotherapy and Immunotherapy

1988
1. The predictive model is validated empirically; a kinetic advantage for i.p. administration of certain antineoplastic drugs exist. 2. The concentrations achieved in the peritoneum are orders of magnitude greater than those found in the plasma, so rate-limiting systemic toxicities may be avoided. 3.
B E, Wolf, P H, Sugarbaker
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Concepts in intraperitoneal chemotherapy

Seminars in Oncology Nursing, 1987
NTRAPERITONEAL (IP) chemotherapy is the administration of chemotherapeutic agents via a catheter into the peritoneal cavity. The chemotherapy is placed in a large volume of fluid, usually 2 L, and infused into the abdominal cavity where it remains for a specified amount of time; then it is usually drained back out the catheter.
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Laparoscopical insertion of intraperitoneal catheters for intraperitoneal chemotherapy

Acta Obstetricia et Gynecologica Scandinavica, 2003
Background and methods.  Eight patients (seven clinically negative stage Ill ovarian cancer and one peritoneal mesothelioma) respectively underwent second‐look laparoscopy for staging, adhesiolysis and insertion of an intraperitoneal catheter and fixation of a portal.
Anaf, Vincent, Gangji, Diamon, Simon, Philippe, Saylam, Keziban   +3 more
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Intraperitoneal chemotherapy for ovarian cancer

Current Oncology Reports, 2003
Intraperitoneal chemotherapy provides a means by which high concentrations of drugs and long durations of tissue exposure can be attained at the peritoneal surface. It has been studied widely in ovarian cancer, a disease in which intra-abdominal progression remains the major source of morbidity and mortality.
Gregory, Friberg, Gini, Fleming
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