Results 291 to 300 of about 158,913 (343)

Chimeric Antigen Receptor T‐Cell Therapy and Autoimmune Diseases in the Nervous System

open access: yesImmunity, Inflammation and Disease, Volume 13, Issue 11, November 2025.
ABSTRACT Introduction Chimeric antigen receptor T‐cell (CAR‐T) therapy, a revolutionary immunotherapy originally developed for hematologic malignancies, has recently gained attention for its potential in treating autoimmune diseases. Increasing evidence suggests that CAR‐T cells can precisely target pathogenic immune populations, offering durable ...
Shun‐yu Yao   +11 more
wiley   +1 more source

New insights into applications of base editor in hereditary disorders

open access: yesInterdisciplinary Medicine, Volume 3, Issue 6, November 2025.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai   +8 more
wiley   +1 more source

The Effect of Intrathecal Dexmedetomidine as an Adjuvant to Spinal Anesthesia: Double Blind Study

open access: hybrid, 2016
Shah Bipin K.   +3 more
openalex   +1 more source

Single‐Cell Analysis of L‐Myc Expressing Neural Stem Cells and Their Extracellular Vesicles Revealed Distinct Progenitor Populations With Neurogenic Potential

open access: yesJournal of Extracellular Biology, Volume 4, Issue 11, November 2025.
ABSTRACT Neural stem cell (NSC)‐based therapies offer a promising strategy to promote brain repair by delivering neurotrophic factors, supporting cell replacement, and stimulating endogenous neurogenesis following injury. While numerous studies have highlighted the protective and regenerative potential of NSCs and their extracellular vesicles (EVs ...
Patrick Pirrotte   +19 more
wiley   +1 more source

Targeting the hypothalamic a11 nucleus to treat parkinsonian-like nociceptive impairments. [PDF]

open access: yesNPJ Parkinsons Dis
Charles KA   +5 more
europepmc   +1 more source

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