Results 311 to 320 of about 158,913 (343)

Acute Chemodenervation of the Bladder With Botulinum Toxin After Spinal Cord Injury Resulted in Preserved Bladder Function in Rodents

Neurourology and Urodynamics, Volume 44, Issue 8, Page 1704-1712, November 2025.
ABSTRACT Despite modern bladder management methods, lower and upper urinary tract complications still contribute significantly to morbidity and diminished quality of life in persons with spinal cord injuries (SCI). Neurogenic overactive bladders often develop after SCI and this can result in loss of compliance, with concomitant urinary tract ...
Noor Al‐Khayat, Lindsay N. Cates, Benjamin R. Valenti, Mark P. Hudson, Claire C. Yang, Zin Z. Khaing   +5 more
wiley   +1 more source

Positive cerebrospinal fluid in the 2024 McDonald criteria for multiple sclerosis. [PDF]

EBioMedicine
Deisenhammer F, Hegen H, Arrambide G, Banwell BL, Coetzee T, Gnanapavan S, Montalban X, Tumani H, Willrich MA, Freedman MS.   +9 more
europepmc   +1 more source

Aliança AMARTE: A Collaborative Network to Improve Oncologic Pediatric Care in Brazil

Pediatric Blood &Cancer, Volume 72, Issue 11, November 2025.
ABSTRACT Introduction In Brazil, inequalities in access to treatment and survival of childhood cancer are observed across different geographic regions. In 2014, under the coordination of Hospital de Câncer Infantojuvenil de Barretos (Fundação Pio XII), six hospitals met weekly for case discussion.
Luiz Fernando Lopes, Patrícia Loggetto, André de Oliveira Junior, Bruna Farias, Carla Nunes, Aline Esmeraldo Andrade de Almeida, Anna Beatriz Costa Neves do Amaral, Anita Frisanco, Carmem Maria Costa Mendonça Fiori, Daniela Santana, Débora Garcia Gasperini, Eliane Francelino, Fabianne Carlesse, Fernanda Crizol Bazaglia, Flora Mitie Watanabe, Isis Quezado Magalhães, Joaquim Caetano de Aguirre Neto, Juliana Teixeira Costa, Karla Emilia de Sá Rodrigues, Mara A. D. Pianovski, Marcelo Milone, Maristella Bergamo Francisco dos Reis, Monnie Abraham, Rosemary Sanz, Seila Prado, Simone de Campos Viera Abib, Thelma Alves de Oliveira, Valdenize Tiziani, Viviany Oliveira Viana, Paola Friedrich, Monika L. Metzger, Carlos Rodriguez‐Galindo   +31 more
wiley   +1 more source

Prognostic impact of central nervous system prophylaxis and a simplified BL model in primary testicular lymphoma: a real-world multicenter study. [PDF]

J Cancer Res Clin Oncol
Liu S, Yang P, Zhao Y, Zhou S, Luo H, Cen X, Dong F, Wan W, Jing H.   +8 more
europepmc   +1 more source

State‐of‐the‐Art on Model‐Informed Drug Development Approaches for Pediatric Rare Diseases

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 11, Page 1743-1759, November 2025.
ABSTRACT Pediatric rare diseases present unique challenges for drug development due to small patient populations, ethical constraints on clinical trial design, and limited prospectively defined natural history data. Model‐Informed Drug Development (MIDD) has emerged as a powerful paradigm to address these challenges by leveraging quantitative methods ...
Rajesh Krishna, Amitava Mitra, Matthew L. Zierhut, Lilly East, Chandra Durairaj   +4 more
wiley   +1 more source

Stiff-Person Syndrome: A Case Report and Treatment Modalities. [PDF]

Cureus
Nguyen J, Musser WB, Hornsby M, Overturf MD, Pathak R.   +4 more
europepmc   +1 more source

The Impact of QSP Modeling on the Design and Optimization of Gene Therapy Approaches

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 11, Page 1760-1764, November 2025.
ABSTRACT Quantitative Systems Pharmacology (QSP) is increasingly utilized to support the design and translation of gene therapies. This perspective outlines the application of QSP modeling across three domains of gene therapy: mRNA‐based therapeutics, adeno‐associated virus (AAV) vectors, and genome editing systems.
Noha Rayad, Ekram A. Chowdhury, Guy M. L. Meno‐Tetang   +2 more
wiley   +1 more source

Efficacy and safety of midazolam compared to fentanyl as adjuvants to hyperbaric bupivacaine in spinal anesthesia: a systematic review and meta-analysis of randomized controlled trials. [PDF]

BMC Anesthesiol
Tadesse MA, Alemu EA, Allene MD, Abebe MM, Alimawu AA, Kebede FS, Wondemu ES.   +6 more
europepmc   +1 more source

Predictors of early disability accumulation in newly diagnosed multiple sclerosis: clinical, imaging and cerebrospinal fluid measures. [PDF]

J Neurol Neurosurg Psychiatry
Lauerer M, Wiltgen T, Brückner C, Engl C, Giglhuber K, Lambrecht S, Pongratz V, Berthele A, Gasperi C, Kirschke JS, Zimmer C, Hemmer B, Mühlau M.   +12 more
europepmc   +1 more source