Results 51 to 60 of about 2,210,556 (241)

Red blood cell alloimmunization and pregnancy: Diagnosis and management

Pregnancy
Red blood cell alloimmunization in pregnancy is a major cause of hemolytic disease of the fetus and neonate (HDFN), which can lead to fetal anemia, hydrops fetalis, and perinatal morbidity and mortality.
Beatrice Valentini, Ruben Ramirez Zegarra, Tullio Ghi, Andrea Dall'Asta   +3 more
doaj   +1 more source

Heterozygous Beta‐Thalassaemia in Pregnancy: Two Rare Causes of Severe Fetal Anemia Requiring Intrauterine Blood Transfusions

Prenatal Diagnosis, EarlyView.
ABSTRACT Aim In this article, we present two cases of severe fetal hemolytic anemia based on a beta‐thalassaemia trait inherited from a single parent. Results These cases, presented at 20 and 28 weeks' gestation, necessitated intra‐uterine blood transfusions.
Eva van der Meij, Frans J. W. Smiers, Tamara T. Koopmann, Ingrid Krapels, Kaatje LePoole, Enrico Lopriore, Johanna M. Middeldorp, Claudia S. Ootjers, Volkher Scharnhorst, Hubertina C. J. Scheepers, Cornelis L. Harteveld, E. J. T. (Joanne) Verweij   +11 more
wiley   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Intrauterine interventions for severe fetal anemia due to parvovirus B19 national outbreak

The Journal of Maternal-Fetal & Neonatal Medicine
Objective Parvovirus B19 infection during pregnancy can cause severe fetal anemia, hydrops fetalis, and fetal death. This study describes our experience managing ten cases of severe fetal anemia due to parvovirus B19 infection during the 2023–2024 ...
Kinneret Tenenbaum-Gavish, Roie Alter, Nir-Ram Duvdevani, Vered Yahalom, Merav Barzilai, Ana Idelson, Mika Shapira Rootman, Anastasia Almog, David Danon, Yuval Gielchinsky   +9 more
doaj   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source

Peri-operative blood transfusion in elective major surgery: incidence, indications and outcome – an observational multicentre study

, 2020
BACKGROUND: Patients' demographic and epidemiological characteristics, local variations in clinicians' knowledge and experience and types of surgery can influence peri-operative transfusion practices.
ALKIŞ, Neslihan, Unal, Dilek, ŞAHAP, MEHMET, TORAMAN, Fevzi, Spahn, Donat R., Polat, Reyhan, Senayli, Yesim   +6 more
core   +2 more sources

Neonatal thrombocytopenia and platelets transfusion

Asian Journal of Transfusion Science, 2012
Background: Neonates often develop thrombocytopenia at some time during hospital stay. Platelet transfusion are frequently given to them and are likely to result in unnecessary transfusion.
Anil K Gupta, Sudarshan Kumari, Abhishek Singhal, Aruna Bahl   +3 more
doaj   +1 more source

Overview of the blood transfusion policy in preterms on the Neonatal Intensive Care Unit [PDF]

, 2013
Preterm infants on the Neonatal Intensive Care Unit receive a greater number of red cell transfusions than any other hospitalised group. Over the past twenty years research has focused on setting standards to determine when it is necessary to transfuse ...
Attard Montalto, Simon, Azzopardi, Eugenio, Said Conti, Valerie, Parascandalo, Raymond, Soler, Paul   +4 more
core  

Intrauterine Transfusions in Fetuses Affected by Parvovirus B19: Complications, Challenges and Outcomes

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir, Emma Van den Eede, Lone N. Nørgaard, Roland Devlieger, Karin Sundberg, Monique C. Haak, Femke Slaghekke   +6 more
wiley   +1 more source

Red cell transfusion triggers in critically ill patients:time for some new TRICCs? [PDF]

, 2010
Current evidence suggests that critically ill patients tolerate anaemia well and that blood transfusions may increase the risk of adverse outcomes. Dr Sakr and colleagues present a contradictory analysis of a surgical ICU cohort, finding an association ...
Walsh, Timothy S; id_orcid, Timothy S Walsh   +1 more
core   +1 more source