ABSTRACT Carbetocin is an oxytocin receptor agonist used for postpartum hemorrhage prevention. While oxytocin is known to transiently prolong the QT/QTc interval, robust QTc data for carbetocin are limited. Carbetocin is known to elevate HR, which can impact QTc analyses; thus, a dose that did not overly elevate HR was important to select.
Daniël M. Jonker +4 more
wiley +1 more source
Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function
ABSTRACT Extracellular vesicles (sEVs) contained in seminal plasma (SP) maintain, in concert with free SP‐components (proteins, hormones, cytokines, metabolites and antioxidants) under an endocrine umbrella the functional in vivo homeostasis of ejaculated spermatozoa. The sEVs define a generic mixture of nanovesicles delivered by male epithelial cells,
Heriberto Rodriguez‐Martinez +3 more
wiley +1 more source
Adults with Long COVID exhibited impaired aerobic capacity and persistent endothelial dysfunction despite preserved myocardial function approximately 3 years after SARS‐CoV‐2 infection. The association between flow‐mediated dilation (FMD) and exercise capacity suggests a potential contribution of peripheral vascular dysfunction to exercise intolerance.
Carla Cristina de Araújo Alves +8 more
wiley +1 more source
Abstract The effects of oral contraceptive pills (OCPs) on metabolism and body composition remain unclear. This study aimed to compare fasting glucose and lipid metabolism between naturally cycling (NAT) females, second‐(OCP2), and third‐generation (OCP3) OCP users during low‐(LH) and high‐hormone (HH) phases.
Claire Karaguesian +3 more
wiley +1 more source
PEBP1 Regulates Ferroptosis in Acute Glaucoma: Targeted Therapy Using Engineered Exosomes
General schematic diagram of Spatial and Single‐Cell Transcriptomics Identifies PEBP1 as a Ferroptosis Mediator in Glaucoma: Targeted Intervention by Engineered Stem Cell Exosomes. ABSTRACT Glaucoma is the leading cause of irreversible blindness worldwide, primarily driven by the progressive loss of retinal ganglion cells (RGCs) under pathological high
Yijia Huang +13 more
wiley +1 more source
Effect of different types of intrauterine devices on intrauterine activity
Objective-To compare the effects of various IUDs on intrauterine activity. Patients and Methods-57 women volunteers aged 18 to 25 in the outpatient clinic of the Department of Obstetrics and Gynecology at Cerrahpasa Medical Faculty of Istanbul University
Alper, T +6 more
core
Factors associated with hysterectomy after failure of levonorgestrel-releasing intrauterine system treatment in women with abnormal uterine bleeding. [PDF]
Erkal N +5 more
europepmc +1 more source
The association between levonorgestrel intrauterine devices and female fertility compared to other contraceptive methods: A historical cohort study. [PDF]
Michaelsen MP +5 more
europepmc +1 more source
Cost-effectiveness of levonorgestrel intrauterine system versus hysteroscopic niche resection for caesarean scar-related spotting in China: an economic evaluation alongside a randomised controlled trial. [PDF]
Zhu C +10 more
europepmc +1 more source

