Results 71 to 80 of about 763 (187)
Acute intermittent hypercapnic hypoxia augments left ventricular contractility
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall +8 more
wiley +1 more source
Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi +12 more
wiley +1 more source
Among 408 sexually active adolescent girls in rural northern Ghana, modern contraceptive use was low (20.8%) despite high awareness (75.2%). Maternal education and information from health workers/teachers were associated with lower use, whereas clinic availability increased use. Interventions must move beyond awareness to address social norms and youth‐
Joseph Lasong +2 more
wiley +1 more source
ABSTRACT Diamond–Blackfan Anemia Syndrome (DBAS) is a rare congenital anemia often requiring chronic red blood cell transfusions from infancy. Without appropriate chelation, iron overload develops early and may be severe; however, no data are available on chelation in patients under 3 years of age.
Francesca Torchio +19 more
wiley +1 more source
Extended HPV typing as an efficient alternative within HPV‐based screening programs
What's New? Extended high‐risk human papillomavirus (hrHPV) typing holds promise for improving cervical intraepithelial neoplasia grade 3 (CIN3) detection, particularly as vaccinated cohorts may shift the prevalence of oncogenic HPV types. The authors of this study evaluated extended hrHPV genotyping within a public screening program involving women ...
Joacim Meneses‐León +11 more
wiley +1 more source
ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen +15 more
wiley +1 more source
ABSTRACT Background In Australia, ultrasonography to confirm gestational age (GA) and pregnancy location is a routine component of early medical abortion (EMA) care. Internationally, protocols have been developed using a history‐based screening tool to identify women not requiring ultrasound.
Catriona Melville, Philip Goldstone
wiley +1 more source
Abstract Background Laparoscopic intrauterine artificial insemination (Lap‐AI) is used in sheep genetic improvement programmes. However, the lambing rate (LR) (i.e., the proportion of inseminated ewes that lamb) following Lap‐AI is variable. Previously, one small UK study investigated factors associated with LR, but it did not adjust for dependencies ...
Mike J. Glover +2 more
wiley +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Evidence of APOE4‐related brain vulnerabilities in verbal memory systems in midlife women
Abstract INTRODUCTION Women carrying the apolipoprotein E4 (APOE4) allele have a greater risk of Alzheimer's disease (AD) from ages 65‐75 years compared to men, yet the effects of APOE4 on cognitive and neuroimaging outcomes among midlife women remain poorly understood.
Katrina A. Wugalter +6 more
wiley +1 more source

