Results 41 to 50 of about 80,139 (294)

Associations between birth size and later height from infancy through adulthood : an individual based pooled analysis of 28 twin cohorts participating in the CODATwins project [PDF]

, 2018
Background: There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment.
Abramson, Lior, Almqvist, Catarina, Bartels, Meike, Bayasgalan, Gombojav, Bjerregaard-Andersen, Morten, Boivin, Michel, Boomsma, Dorret I, Brandt, Ingunn, Brendgen, Mara, Brescianini, Sonia, Burt, S Alexandra, Corley, Robin P, Craig, Jeffrey M, Cutler, Tessa L, Derom, Catherine, Dionne, Ginette, Dubois, Lise, Fagnani, Corrado, Fisher, Abigail, Harris, Jennifer R, Haworth, Claire MA, Heikkila, Kauko, Hopper, John L, Huibregtse, Brooke M, Hur, Yoon-Mi, Jelenkovic, Aline, Ji, Fuling, Kaprio, Jaakko, Kim, Jina, Klump, Kelly L, Knafo-Noam, Ariel, Krueger, Robert F, Lee, Jooyeon, Lee, Sooji, Llewellyn, Clare H, Loos, Ruth JF, Magnusson, Patrik KE, Mankuta, David, McGue, Matt, Narandalai, Danshiitsoodol, Nelson, Tracy L, Nielsen, Henning Beck, Nilsen, Thomas Sevenius, Ning, Feng, Ooki, Syuichi, Pahlen, Shandell, Pang, Zengchang, Pietilainen, Kirsi H, Plomin, Robert, Rasmussen, Finn, Rebato, Esther, Saffery, Richard, Saudino, Kimberly J, Silventoinen, Karri, Sodemann, Morten, Sorensen, Thorkild IA, Stazi, Maria A, Sund, Reijo, Sung, Joohon, Tarnoki, Adam D, Tarnoki, David L, Tynelius, Per, Ullemar, Vilhelmina, van Beijsterveld, Catharina EM, Vitaro, Frank, Vlietinck, Robert F, Whitfield, Keith E, Willemsen, Gonneke, Yokoyama, Yoshie   +68 more
core   +6 more sources

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Parameters Associated with Adverse Fetal Outcomes in Parvovirus B19 Congenital Infection [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2017
Objective To investigate the clinical and sonographic parameters associated with adverse fetal outcomes in patients with congenital parvovirus B19 infection managed by intrauterine transfusion.
Isabela Karine Rodrigues Agra, Antonio Gomes Amorim Filho, Lawrence Hsu Lin, Sckarlet Ernandes Biancolin, Rossana Pulcineli Vieira Francisco, Maria de Lourdes Brizot   +5 more
doaj   +1 more source

Maternal obesity during pregnancy and premature mortality from cardiovascular event in adult offspring : follow-up of 1 323 275 person years [PDF]

, 2013
Peer reviewedPublisher ...
Allan, Keith M, Bhattacharya, Siladitya, Bhattacharya, Sohinee, Hannaford, Philip C, Lee, Amanda J, McNeill, Geraldine, Norman, Jane E, Raja, Edwin A, Reynolds, Rebecca M, Sarwar, Nadeem   +9 more
core   +4 more sources

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Intrauterine Transmission of SARS-CoV-2

Emerging Infectious Diseases, 2021
We documented fetal death associated with intrauterine transmission of severe acute respiratory syndrome coronavirus 2. We found chronic histiocytic intervillositis, maternal and fetal vascular malperfusion, microglial hyperplasia, and lymphocytic ...
Emanuele T. S. Stonoga, Laura de Almeida Lanzoni, Patricia Zadorosnei Rebutini, André Luiz Permegiani de Oliveira, Jullie Anne Chiste, Cyllian Arias Fugaça, Daniele M. M. Prá, Ana Paula Percicote, Andrea Rossoni, Meri Bordignon Nogueira, Lucia de Noronha, Sonia Mara Raboni   +11 more
doaj   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Outcome of Fetal Dysrhythmias with and without Extracardiac Anomalies

Diagnostics, 2023
Fetal dysrhythmias are common abnormalities, which can be categorized into three types: rhythm irregularities, tachyarrhythmias, and bradyarrhythmias. Fetal arrhythmias, especially in high-risk pregnancies, require special monitoring and treatment.
Stephanie Springer, Eva Karner, Elisabeth Seidl-Mlczoch, Guelen Yerlikaya-Schatten, Petra Pateisky, Barbara Ulm   +5 more
doaj   +1 more source

Caspase‐3/GSDME‐Mediated Trophoblast Pyroptosis and Reciprocal Macrophage Polarization Contribute to Inflammation in Early‐Onset Preeclampsia

Advanced Science, EarlyView.
In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang, Weinan Deng, Shilei Bi, Yifan Wang, Zhaowei Tu, Lijun Huang, Lili Du, Lizi Zhang, Zhoushan Feng, Wei Sun, Tengfei Liu, Julia Kzhyshkowska, Haibin Wang, Jingsi Chen, Dunjin Chen, Shuang Zhang   +15 more
wiley   +1 more source

Is birthweight associated with total and aggressive/lethal prostate cancer risks? A systematic review and meta-analysis [PDF]

, 2016
BACKGROUND: It has been hypothesised that intrauterine exposures are important for subsequent prostate cancer risk. Prior epidemiological studies have used birthweight as a proxy of cumulative intrauterine exposures to test this hypothesis, but results ...
Cook, Michael B, Hardy, Rebecca, Kuh, Diana, Mackinnon, Karen, Sutcliffe, Siobhan, Welsh, Judith, Zhou, Cindy Ke   +6 more
core   +3 more sources