Results 41 to 50 of about 5,347,369 (278)

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Intrauterine Growth Restriction Associated with Hematologic Abnormalities: Probable Manifestations of Placental Mesenchymal Dysplasia

American Journal of Perinatology Reports, 2015
Introduction Placental mesenchymal dysplasia is a rare vascular disease associated with intrauterine growth restriction, fetal demise as well as Beckwith–Wiedemann syndrome.
Cristina Martinez-Payo, Rocio Alvarez Bernabeu, Isabel Salas Villar, Enrique Iglesias Goy   +3 more
doaj   +1 more source

Pre-Eclampsia and Intrauterine Growth Restriction (IUGR)Prevention– Is Enoxaparin an Effective Option

Pakistan Armed Forces Medical Journal, 2022
Objective: To determine the effectiveness of Enoxaparin in preventing pre-eclampsia and intrauterine growth restriction in women with the history of pre-eclampsia and IUGR in an earlier pregnancy. Study Design: Quasi-Experimental Study.
Saira Saeed, Shafia Barkat, Badar Murtaza   +2 more
doaj   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

Advanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu, Xinkui Liu, Xiaoyan Yu, Qiaoqiao Han, Feifei Shi, Weiwei Song, Lu Liu, Chu Chu, Chenyang Shen, Zhen Zhang, Xia Li   +10 more
wiley   +1 more source

Editorial: Intrauterine growth restriction: screening and outcomes [PDF]

Frontiers in Physiology
Intrauterine growth restriction (IUGR) is a condition in which the fetus does notachieve its full growth potential, resulting in low birthweight infants.
Claire Stenhouse, F. Xavier Donadeu, Fernanda R. C. L. Almeida   +2 more
doaj   +2 more sources

Parental factors associated with intrauterine growth restriction [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2015
Introduction. Linear growth failure is caused by multiple factors including parental factors. Objective. The aim of this study was to evaluate parental risk factors for intrauterine growth restriction (IUGR) on a population of Romanian newborn ...
Hăşmăşanu Monica G., Bolboacă Sorana D., Drugan Tudor C., Matyas Melinda, Zaharie Gabriela C.   +4 more
doaj   +1 more source

A new phenotipical variant of intrauterine growth restriction?

, 2007
OBJECTIVES: A link between intrauterine growth restriction and major adult-onset diseases has been reported. In this study we observed a series of hitherto-unrecognized clinical features in a population of children with intrauterine growth restriction.
Daniele Costantini, TONNI, G., JAUBERT, F., Claudio DeFelice, LATINI, G., Mirella Strambi, Mattia Gentile, Giuseppe Latini, TASSI, R., QUARTULLI, L., Gabriele Tonni, DE CAPUA, R., COSTANTINI, D., Francis Jaubert, STRAMBI, M., Bruno De Capua, DE FELICE, C., GENTILE, M., Rossana Tassi, Lorenzo Quartulli   +19 more
core   +1 more source

Heterozygous Variants in LRP1 Cause a Neurodevelopmental Disorder With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT LRP1 encodes the low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1), a transmembrane protein involved in endocytosis and activation of multiple signaling pathways. LRP1 variants have been implicated in the pathogenesis of congenital heart defects (CHD), Alzheimer's disease, and neurodevelopmental disorders (NDD).
Alyssa L. Rippert, Gudny Anna Arnadottir, Laura Bedinger, Nicola Brunetti‐Pierri, Jennifer Cech, Xin Chen, Yanmin Chen, Erika Chick, Sarah Dyack, Madeleine Franchi, Tanja Frey, David Genevieve, Ian Glass, Jorge Granadillo, Kelly A. Keener, Sara B. MacKay, Paige McDunnah, Vinod K. Misra, Kristin G. Monaghan, Sureni V. Mullegama, Cristina Peduto, Leia Peterman‐Prather, Anita Rauch, Cherith Somerville, Kari Stefansson, Katharina Steindl, Patrick Sulem, Telma Sulem, Pamela Trapane, Roberta Zeuli, Samuel Zinner, Kosuke Izumi   +31 more
wiley   +1 more source

Litter-size-dependent intrauterine growth restriction in sheep

Animal, 2007
Regulation of foetal development in sheep depends on interactions between the intrinsic capacity of the foetus for growth and the maternal environment.
E. Gootwine, T.E. Spencer, F.W. Bazer
doaj   +1 more source

A Rare Form of Microcephalic Primordial Dwarfism due to NSMCE2 Deficiency (Seckel Syndrome Type 10): A Report of Macular Involvement

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto, Céline Huber, Clément Paya, Isabelle Audo, Nathalie Boddaert, Valérie Cormier‐Daire   +5 more
wiley   +1 more source