Results 101 to 110 of about 6,369,333 (348)

Quantitative Coronary Angiography Guidance for Drug‐Eluting Stent Implantation: A Narrative Review

open access: yesHealth Science Reports
Background Percutaneous coronary intervention (PCI) using drug‐eluting stents is an established strategy for the treatment of significant obstructive coronary artery disease.
Cheol Whan Lee   +3 more
doaj   +1 more source

Impact and trends of intravascular imaging in diagnostic coronary angiography and percutaneous coronary intervention in inpatients in the United States

open access: yesCatheterization and cardiovascular interventions, 2018
Intravascular imaging with intravascular ultrasound (IVUS) and optical coherence tomography (OCT) is an important adjunct to invasive coronary angiography.
N. Smilowitz   +4 more
semanticscholar   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

Debate: Intravascular ultrasound and optical coherence tomography in percutaneous revascularization. The OCT expert perspective

open access: yesREC: Interventional Cardiology (English Ed.), 2020
QUESTION: Do you think there is enough evidence to indicate the use of intravascular imaging during percutaneous coronary interventions? ANSWER: Currently, there is enough evidence on the benefits provided by intracoronary imaging modalities during ...
Nieves Gonzalo
doaj   +1 more source

Assessment of coronary artery outward remodeling in consequence of excision of epicardial adipose tissue in Ossabaw swine [PDF]

open access: yes, 2017
Background Coronary artery disease (CAD) results from the buildup of cholesterol, inflammatory factors, and proliferating smooth muscle cells within a vessel wall. This plaque impedes on the vessel lumen, decreasing the space through which blood can flow,
Coderre, Kelly
core   +1 more source

Multimodal intravascular imaging technology for characterization of atherosclerosis

open access: yesJournal of Innovative Optical Health Sciences, 2019
Early detection of vulnerable plaques is the critical step in the prevention of acute coronary events. Morphology, composition, and mechanical property of a coronary artery have been demonstrated to be the key characteristics for the identification of ...
Yan Li, Jason J. Chen, Zhongping Chen
semanticscholar   +1 more source

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