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Platinum Accumulation and Cancer-Related Fatigue, Correlation With IL-8, TNF-α and Hemocytes

open access: yesFrontiers in Pharmacology, 2021
Platinum-based chemotherapy drugs cause platinum accumulation and result in cancer-related fatigue (CRF), which is related to immune response through still ambiguous mechanisms.
Yuling Zhang   +5 more
doaj   +1 more source

Intravenous methylcobalamin effectively ameliorated painful diabetic neuropathy: A randomized double-blind placebo controlled trial [PDF]

open access: yesRomanian Journal of Neurology, 2021
Objective. Painful diabetic neuropathy (PDN) is a prevalent debilitating consequence of diabetes mellitus with lack of satisfactory therapeutic options. Methylcobalamin (MeCbl) is one of vitamin B12 analogs with known neurotrophic effects.
Thomas Eko Purwata   +5 more
doaj   +1 more source

Pharmacokinetic interaction between rhynchopylline and pellodendrine via CYP450 enzymes and P-gp

open access: yesPharmaceutical Biology, 2021
Context Rhynchopylline and pellodendrine are major extractions of commonly used Chinese medicine in gynaecology. The interaction between these two compounds could affect treatment efficiency and even result in toxicity during their co-administration in ...
Qingzhen Meng, Yongheng Cheng, Cui Zhou
doaj   +1 more source

Intercellular Communication Reveals Therapeutic Potential of Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer

open access: yesBiomolecules, 2022
(1) Background: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with high intra-tumoral heterogeneity. The epithelial-mesenchymal transition (EMT) is one of the inducers of cancer metastasis and migration.
Yang Liu   +5 more
doaj   +1 more source

Nursing of recurrent malposition of peripherally inserted central catheters in a patient with thoracic outlet syndrome and related nursing measures (1例胸廓出口综合征患者经外周静脉置入中心静脉导管置管反复原发性异位的护理)

open access: yes中西医结合护理, 2022
This paper summarized the potential causes and nursing measures of recurrent malposition of peripherally inserted central catheters (PICC) in a patient with thoracic outlet syndrome and related nursing measures.
ZHANG Liuyan (张柳燕)   +2 more
doaj   +1 more source

Effects of Low Dose Dexmedetomidine Infusion on Intraoperative Haemodynamic Stress Response in Patients Undergoing Oral Oncological Surgeries: A Randomised Control Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Maintaining stable haemodynamics throughout oral and maxillofacial surgeries helps to decrease intraoperative bleeding and thus improves the surgical field avoiding unnecessary damage to vital structures and tissues.
Gifty Susan Philip   +2 more
doaj   +1 more source

Use of closed systems in the Hospital Pharmacy [PDF]

open access: yesFarmacia Hospitalaria, 2016
Objective: In the setting of the increasing use of closed systems for reconstitution and preparation of these drugs, we intend to analyze the correct use of these systems in the Hospital Pharmacy, with the objective to minimize the risks of exposure not ...
María Forte Pérez-Minayo   +5 more
doaj   +1 more source

Prevention of pain with the injection of microemulsion propofol: a comparison of a combination of lidocaine and ketamine with lidocaine or ketamine alone [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
BackgroundAquafol, a microemulsion propofol, causes more severe and frequent pain on injection than propofol. The purpose of this study was to compare a combination of lidocaine and ketamine on aquafol-induced pain with lidocaine or ketamine alone during
Insung Hwang   +6 more
doaj   +1 more source

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