This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan+6 more
wiley +1 more source
Intravenous Magnesium Sulphate as an Adjuvant Therapy for Acute Exacerbations of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis. [PDF]
Farid T+15 more
europepmc +1 more source
Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity
This study uncovers a spatiotemporal regulation of STING activity by linear ubiquitination in antiviral immunity. At the early stage of the infection, LUBAC promotes STING linear ubiquitination to drive its trafficking from the ER to the Golgi apparatus for activation.
Yong Zhang+13 more
wiley +1 more source
The First Case of a Single-Dose, Intravenous Perampanel Administration for Early Postoperative Seizure Prophylaxis. [PDF]
Sugii N, Yamada T, Ishikawa E.
europepmc +1 more source
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li+11 more
wiley +1 more source
Intravenous Medication Administration Errors in Hospitalised Patients: An Updated Systematic Review. [PDF]
Rajakumar S+4 more
europepmc +1 more source
Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li+11 more
wiley +1 more source
An infant with IVIG-resistant Kawasaki disease requiring repeated glucocorticoids therapy: A case report and literature review. [PDF]
Ren Y.
europepmc +1 more source
An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy
This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma+14 more
wiley +1 more source