Results 61 to 70 of about 910,740 (223)

Offspring of prenatal IV nicotine exposure exhibit increased sensitivity to the reinforcing effects of methamphetamine

open access: yesFrontiers in Pharmacology, 2012
Maternal smoking during pregnancy is associated with increased substance abuse in offspring. Preclinical research shows that in utero exposure to nicotine, the primary psychoactive compound in tobacco smoke, influences the neurodevelopment of reward ...
Steven Brown Harrod   +2 more
doaj   +1 more source

Optimal Sepsis Patient Treatment using Human-in-the-loop Artificial Intelligence [PDF]

open access: yesarXiv, 2020
Sepsis is one of the leading causes of death in Intensive Care Units (ICU). The strategy for treating sepsis involves the infusion of intravenous (IV) fluids and administration of antibiotics. Determining the optimal quantity of IV fluids is a challenging problem due to the complexity of a patient's physiology.
arxiv  

On separation of time scales in pharmacokinetics [PDF]

open access: yesarXiv, 2012
A lot of criticism against the standard formulation of pharmacokinetics has been raised by several authors. It seems that the natural reaction for that criticism is to comment it from the point of view of the theory of conservation laws. Simple example of balance equations for the intravenous administration of drug has been given in 2011 and the ...
arxiv  

Soft Null Hypotheses: A Case Study of Image Enhancement Detection in Brain Lesions [PDF]

open access: yesarXiv, 2013
This work is motivated by a study of a population of multiple sclerosis (MS) patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify active brain lesions. At each visit, a contrast agent is administered intravenously to a subject and a series of images is acquired to reveal the location and activity of MS lesions ...
arxiv  

Study on the quality of drug vial recognition and grasping and opening for pharmacy intravenous admixture robot based on nanophotonic sensing

open access: yesSLAS Technology
With the continuous progress of medical technology, traditional medicine bottle identification and management methods have problems such as low efficiency and large errors, and innovative solutions are urgently needed.
Li Guochun   +6 more
doaj  

Optimizing Sequential Medical Treatments with Auto-Encoding Heuristic Search in POMDPs [PDF]

open access: yesarXiv, 2019
Health-related data is noisy and stochastic in implying the true physiological states of patients, limiting information contained in single-moment observations for sequential clinical decision making. We model patient-clinician interactions as partially observable Markov decision processes (POMDPs) and optimize sequential treatment based on belief ...
arxiv  

Development of a high-resolution and high efficiency Single Photon detector for studying cardiovascular diseases in mice [PDF]

open access: yesarXiv, 2019
SPECT systems using pinhole apertures permit radiolabeled molecular distributions to be imaged in vivo in small animals. Nevertheless studying cardiovascular diseases by means of small animal models is very challenging. Specifically, submillimeter spatial resolution, good energy resolution and high sensitivity are required. We designed what we consider
arxiv  

Closed-Loop Intravenous Drug Administration Using Photoplethysmography

open access: yesIEEE Journal of Translational Engineering in Health and Medicine, 2018
An optically-based injection control system has been developed for preclinical use for an intravenous drug delivery application. Current clinical drug delivery for oncology typically provides for intravenous administration without an awareness of ...
George W. Carpenter   +4 more
doaj   +1 more source

THE EFFECT OF INTRAVENOUS INFUSION OF THROMBOPLASTIN ON “HEPARIN TOLERANCE” 1 [PDF]

open access: bronze, 1951
Robert C. Hartmann   +4 more
openalex   +1 more source

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