The clinical pharmacology of intranasal l-methamphetamine. [PDF]
BackgroundWe studied the pharmacology of l-methamphetamine, the less abused isomer, when used as a nasal decongestant.Methods12 subjects self-administered l-methamphetamine from a nonprescription inhaler at the recommended dose (16 inhalations over 6 ...
Everhart, Tom +6 more
core +2 more sources
Perioperative intravenous ketamine for acute postoperative pain in adults.
BACKGROUND Inadequate pain management after surgery increases the risk of postoperative complications and may predispose for chronic postsurgical pain.
E. Brinck +6 more
semanticscholar +1 more source
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser +6 more
wiley +1 more source
Paeoniflorin improves atherosclerosis by regulating the gut microbiota and fecal metabolites
Atherosclerosis (AS) is a chronic inflammatory disease and a key factor in cardiovascular disease. Paeoniflorin (PF), a monomer component extracted from red and white paeony roots, has been used for the prevention and treatment of cardiovascular diseases,
Mengyao Xia +7 more
doaj +1 more source
Pain on Injection of MCT/LCT Preparations of Propofol and Etomidate: A Double-blind Randomised Comparative Study [PDF]
Introduction: Propofol and etomidate are both very popular in routine practice as they have very rapid onset and offset of action when used as intravenous agents. Both these drugs have newer Medium Chain Triglyceride and Long Chain Triglyceride (MCT/LCT)
Harsaprava Dutta +2 more
doaj +1 more source
The Advent Of Cytomegalovirus Infection In HIV Infected Patients: A review [PDF]
Cytomegalovirus is considered as one among the long list of latent infections in humans that although normally controlled by the cellular immune response, gets activated after HIV infection takes its role on infecting the T4 lymphocytes. Clinical disease
Kirubakaran Isaac, Dr Sundar
core +1 more source
Anticoagulants for acute ischaemic stroke [PDF]
Peer reviewedPublisher ...
Counsell, Carl +2 more
core +1 more source
Use of Short Peripheral Intravenous Catheters: Characteristics, Management, and Outcomes Worldwide.
BACKGROUND Peripheral intravenous catheter (PIVC) use in health care is common worldwide. Failure of PIVCs is also common, resulting in premature removal and replacement.
E. Alexandrou +9 more
semanticscholar +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Oral rehydration versus intravenous therapy for treating dehydration due to gastroenteritis in children: a meta-analysis of randomised controlled trials [PDF]
BACKGROUND: Despite treatment recommendations from various organizations, oral rehydration therapy (ORT) continues to be underused, particularly by physicians in high-income countries.
A Mackenzie +47 more
core +2 more sources

