Results 91 to 100 of about 1,116,406 (351)
Profile of sugammadex for reversal of neuromuscular blockade in the elderly: Current perspectives [PDF]
The number of elderly patients is increasing worldwide. This will have a significant impact on the practice of anesthesia in future decades. Anesthesiologists must provide care for an increasing number of elderly patients, who have an elevated risk of ...
Bertoncello, Francesco+2 more
core +1 more source
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu+5 more
wiley +1 more source
Enhanced recovery after surgery [PDF]
Enhanced Recovery or Fast Track Recovery after Surgery protocols (ERAS) have significantly changed perioperative care following colorectal surgery and are promoted as reducing the stress response to surgery.
Horgan, Paul G.+3 more
core +1 more source
Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li+8 more
wiley +1 more source
Effects of intrathecal opioids use in cesarean section on breastfeeding and newborns’ weight gaining [PDF]
Objective: To assess the association between intrapartum intrathecal opioid use and breastfeeding and weight gain following cesarean section. Materials and methods: The prospective double-blinded study was conducted on term pregnant women, undergoing ...
Anbarafshan, Mohammad+6 more
core +1 more source
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo+3 more
wiley +1 more source
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng+7 more
wiley +1 more source
Alfaxone TIVA bij de chirurgische excisie van een tracheaal adenocarcinoma bij een kat [PDF]
A ten-year-old European Shorthair cat was presented with complaints of progressively worsening dyspnea with open-mouth breathing and inspiratory and expiratory stridor.
Bosmans, Tim+6 more
core +1 more source
A modular and customizable RNAi therapeutics delivery platform composed of a pseudosymmetric human RNA binding protein‐siRNA complex (SmiRNP) is developed. By fusing a targeting module and an endosomal escape peptide onto the delivery platform, SmiRNP successfully delivered siRNA to silence the KRAS oncogene in a colorectal carcinoma cell line, leading
Nok Yin Tam+9 more
wiley +1 more source
ELECTROCARDIOGRAPHIC STUDIES DURING ENDOTRACHEAL INTUBATION. II. EFFECTS DURING GENERAL ANESTHESIA AND INTRAVENOUS PROCAINE [PDF]
CHARLES L. BURSTEIN+2 more
openalex +1 more source