Results 61 to 70 of about 486,193 (301)

Retrospective analysis of anesthesia for deep brain electrical stimulation in movement disorders

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2011
Objective To analyze the merits and demerits, and main points of anesthetic management of different anesthesia regimens for deep brain stimulation (DBS) in movement disorders.
Zhaolong TIAN   +3 more
doaj  

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Effects of opioid-free total intravenous anesthesia on postoperative nausea and vomiting after treatments of lower extremity wounds: protocol for a randomized double-blind crossover trial

open access: yesPerioperative Medicine, 2023
Background Postoperative nausea and vomiting (PONV) are common after general anesthesia and surgery. This study aims to compare the effects of total intravenous opioid-free anesthesia (OFA) with conventional opioid-based anesthesia (OBA) on PONV in ...
Ya-juan Zhu   +6 more
doaj   +1 more source

Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle

open access: yesAdvanced Functional Materials, EarlyView.
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang   +18 more
wiley   +1 more source

Retrospective study on patient comfort and post-operative condition associated with intravenous sedation versus general anesthesia for third molar extraction in ambulatory surgery in a state hospital

open access: yesJournal of Oral Medicine and Oral Surgery
Objectives: Third molar extraction requires local or general anesthesia. In public hospitals, general anaesthesia is frequently used to perform the most complex extractions and to accommodate patients' wishes. However, the choice of general anesthesia is
Légroz Eloise   +2 more
doaj   +1 more source

Effect of intravenous dexamethasone in dimishing alfentanyl-induced-cough [PDF]

open access: yes
Background & objectives: The use of synthetic opioids (fentanil, alfentanil, …) has been increasing as they can induce anesthesia without histamine release to the stress caused by anesthesia and can cause an effective analgesia at first cut.
نوروزی, ودود   +1 more
core  

Department of Anesthesia. University of Iowa. Spring 2009. [PDF]

open access: yes, 2009
University of Iowa Department of Anesthesia ...

core  

Immediate-Type Hypersensitivity to Succinylated Corticosteroids [PDF]

open access: yes, 2010
Background: Despite their frequent use, systemic corticosteroids have rarely elicited immediate-type reactions. Objective: We report two male patients, aged 26 and 70 years, respectively, with severe immediate-type hypersensitivity secondary to the ...
Raewer, Helen-Caroline   +7 more
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

open access: yesAdvanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal   +21 more
wiley   +1 more source

Deep sedation in patients undergoing atrioventricular nodal reentry tachycardia ablation

open access: yesResearch in Cardiovascular Medicine, 2013
Background: General anesthesia and deep sedation can be used during cardiac EPS to relief pain and provide comfort and immobility, but many electrophysiologists avoid sedation for better arrhythmia induction. Objective: To determine anesthesia effects in
Amirfarjam Fazelifar   +8 more
doaj   +1 more source

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