Results 91 to 100 of about 4,963,319 (355)

How patterns of injecting drug use evolve in a cohort of people who inject drugs [PDF]

This research found an overall movement away from street based drug purchasing and drug use, towards more activity in private settings, which has important implications for the harms experienced by people who inject drugs.
Alison Ritter, Jonathan P. Caulkins, Nick Scott, Paul Dietze   +3 more
core  

Comparative effectiveness of drugs used to constrict the patent ductus arteriosus: a secondary analysis of the PDA-TOLERATE trial (NCT01958320). [PDF]

, 2019
ObjectiveTo evaluate the effectiveness of drugs used to constrict patent ductus arteriosus (PDA) in newborns < 28 weeks.MethodsWe performed a secondary analysis of the multi-center PDA-TOLERATE trial (NCT01958320).
Aucott, Susan W, Bulbul, Ali, Carey, William A, Clyman, Ronald I, Derrick, Matthew, Dong, Lawrence, Erdeve, Omer, Farooqi, Aijaz, Hassinger, Denise C, Hayashi, Madoka, Heuchan, Anne Marie, Håkansson, Stellan, Kaempf, Joseph, Katheria, Anup, Kimball, Amy, Leone, Tina, Liebowitz, Melissa, Lindqvist, Johanna, Nelson, Kelly, Perez, Jorge, Sankar, Meera, Sauberan, Jason, Serize, Arturo, Singh, Jaideep, Wickremasinghe, Andrea, Wolf, Ilene Sue   +25 more
core   +1 more source

Nitrates for the Management of Acute Heart Failure Syndromes, A Systematic Review [PDF]

, 2016
© The Author(s) 2016Intravenous nitrates are widely used in the management of acute heart failure syndrome (AHFS) yet with lack of robust evidence to support their use.
Farag, Mohamed, Gorog, Diana A, Shoaib, Ahmad   +2 more
core   +2 more sources

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile

International Journal of Nanomedicine, 2017
Docetaxel is a highly potent anticancer agent being used in a wide spectrum of cancer types. There are important matters of concern regarding the drug’s pharmacokinetics related to the conventional formulation.
Pedram Rafiei, A. Haddadi
semanticscholar   +1 more source

Survival After Intravenous Versus Intraosseous Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Shock-Refractory Cardiac Arrest

Circulation, 2020
Supplemental Digital Content is available in the text. Background: Antiarrhythmic drugs have not proven to significantly improve overall survival after out-of-hospital cardiac arrest from shock-refractory ventricular fibrillation/pulseless ventricular ...
M. Daya, B. Leroux, P. Dorian, T. Rea, C. Newgard, L. Morrison, J. Lupton, J. Menegazzi, J. Ornato, G. Sopko, J. Christenson, A. Idris, P. Mody, G. Vilke, Caroline Herdeman, D. Barbic, P. Kudenchuk   +16 more
semanticscholar   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

An in vitro study to determine the impact of lipid emulsion on partitioning of a broad spectrum of drugs associated with overdose

BJA Open
Background: Intravenous lipid emulsion is recognised as a therapy for rescue in cases of local anaesthetic toxicity, but its use in reversing overdose or toxicity related to other drugs remains the subject of debate.
Kenneth Barker, Michael Stewart, Alison Rutter, Phillip D. Whitfield, Ian L. Megson   +4 more
doaj   +1 more source

Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]

, 2016
AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F, Dale, R. C., Hong, M, Jones, H, Mohammad, Ss, Nosadini, M, Pillai, Sc, Sharpe, C   +7 more
core   +1 more source

Randomized Placebo‐Controlled Trial of Intravenous Immunoglobulin in Autoimmune LGI1/CASPR2 Epilepsy

Annals of Neurology, 2019
Drug‐resistant seizures are common in patients with leucine‐rich, glioma‐inactivated 1 (LGI1)‐IgG associated and contactin‐associated protein‐like 2 (CASPR2)‐IgG associated encephalitis.
D. Dubey, J. Britton, A. McKeon, A. Gadoth, A. Zekeridou, Sebastian Lopez Chiriboga, M. Devine, J. Cerhan, K. Dunlay, J. Sagen, Melanie Ramberger, P. Waters, S. Irani, S. Pittock   +13 more
semanticscholar   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source