Results 191 to 200 of about 72,783 (273)

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

Advanced Science, EarlyView.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang, Xiangxu Kong, Wei Wang, Huaxin Zhou, Haoran Qu, Zhengyao Guan, Honglei Wu, Xiangyu Zhai, Bin Jin   +8 more
wiley   +1 more source

Effects of Rate of Infusion and Probenecid on Serum Levels, Renal Excretion, and Tolerance of Intravenous Doses of Cefoxitin in Humans: Comparison with Cephalothin [PDF]

, 1974
C. S. Goodwin, E. B. Raftery, A.David Goldberg, Helen R. Skeggs, A. E. Till, Christine M. Martin   +5 more
openalex   +1 more source

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source

The effect on drinking in the rat of intravenous infusion of angiotensin, given alone or in combination with other stimuli of thirst

, 1969
J. T. Fitzsimons, Barbara J. Simons
openalex   +2 more sources

Semaphorin 3E–Plexin D1 Axis Drives Lung Fibrosis through ErbB2‐Mediated Fibroblast Activation

Advanced Science, EarlyView.
TGF‐β1 stimulation in fibroblasts leads to increased Furin expression, Furin‐mediated cleavage of P87‐Sema3E to P61‐Sema3E, which affects fibroblast function through the autocrine pathway, and the P61‐Sema3E‐PlexinD1 axis promotes fibroblast activation, proliferation and migration by affecting ErbB2 phosphorylation, which in turn activates the ErbB2 ...
Zhesong Deng, Jinkun Chen, Ruonan Yang, Yuan Zhan, Shanshan Chen, Jiaheng Zhang, Hao Fu, Yiya Gu, Qian Huang, Jixing Wu, Lianyu Shan, Abdelilah Soussi Gounni, Jungang Xie   +12 more
wiley   +1 more source

Effects of intravenous infusion of potassium chloride on potassium and sodium excretion and on the rate of urine formation in the cow

, 1962
Ronald S. Anderson, E. C. Pickering
openalex   +2 more sources

Gentamicin Intravenous Infusion Rate: Effect on Interstitial Fluid Concentration [PDF]

, 1977
Alan J. Kozak, Dale N. Gerding, Lance R. Peterson, Wendell H. Hall   +3 more
openalex   +1 more source

Rapid Blood Clot Removal via Remote Delamination and Magnetization of Clot Debris

Advanced Science, EarlyView.
A programmable colloidal microswarm is developed to quickly detach blood clots and enable rapid recanalization, with the detached debris functioning as a magnetic “debris‐robot” that can be efficiently propelled and retrieved via catheter suction, which could significantly save time compared to the critical “Golden 6 hours” window for ischemic stroke ...
Qinglong Wang, Ben Wang, Kai Fung Chan, Xin Song, Qianqian Wang, Fengtong Ji, Lin Su, Bonaventure Yiu Ming Ip, Ho Ko, Philip Wai Yan Chiu, Thomas Wai Hong Leung, Li Zhang   +11 more
wiley   +1 more source

Efficacy of intravenous infusions of UC-derived MSCs for the treatment of COVID-19: A structured summary of a phase II double blinded, randomized controlled clinical trial

, 2020
Ali M, Mehmood A, Tarar MN, Nawaz Z, Riazuddin SA, Khan A, Riazuddin S.   +6 more
europepmc   +1 more source

Effect of intravenous infusion of acetylsalicyclic acid on renal function. [PDF]

, 1972
M Robert, J P Fillastre, H. H. Berger, H Malandain   +3 more
openalex   +1 more source