Results 51 to 60 of about 72,783 (273)
KITLM: Domain-Specific Knowledge InTegration into Language Models for Question Answering [PDF]
arXiv, 2023 Large language models (LLMs) have demonstrated remarkable performance in a wide range of natural language tasks. However, as these models continue to grow in size, they face significant challenges in terms of computational costs. Additionally, LLMs often lack efficient domain-specific understanding, which is particularly crucial in specialized fields ...
arxiv
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Music interventions have been shown to have beneficial effects on hemodynamic parameters, pain, and anxiety in various medical settings. However, music interventions in the setting of acute stroke have not been studied. The objective of this trial was to perform a pilot feasibility study of music interventions in the setting of acute
Jeffrey J. Fletcher +7 more
wiley +1 more source
BMJ Open, 2019 Background Intravenous insulin infusions are considered the treatment of choice for critically ill patients and non-critically ill patients with persistent raised blood glucose who are unable to eat, to achieve optimal blood glucose levels.
Rick Iedema +4 more
doaj +1 more source
Phase 1, First‐In‐Human, Single‐/Multiple‐Ascending Dose Study of Iluzanebart in Healthy Volunteers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of iluzanebart, a fully human monoclonal antibody TREM2 (triggering receptor expressed on myeloid cells 2) agonist, after single‐ (SAD) and multiple‐ascending‐dose (MAD) administration.
Andreas Meier +8 more
wiley +1 more source
A Deep Neural Network -- Mechanistic Hybrid Model to Predict Pharmacokinetics in Rat [PDF]
arXiv, 2023 An important aspect in the development of small molecules as drugs or agro-chemicals is their systemic availability after intravenous and oral administration. The prediction of the systemic availability from the chemical structure of a potential candidate is highly desirable, as it allows to focus the drug or agrochemical development on compounds with ...
arxiv
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Ofatumumab, a fully human anti‐CD20 monoclonal antibody, is effective in reducing relapses and disability progression in patients with multiple sclerosis. This study aimed to examine immune profile changes associated with ofatumumab in a prospective cohort of Chinese patients with relapsing–remitting multiple ...
Shu Yang +9 more
wiley +1 more source
Clinical Informatics: Recursive Concurrence Intravenous Medication Administration Systems Protocols for Addressing the Potential Problem of Recessive Lethal Autonomy in Smart Infusion Systems [PDF]
arXiv, 2016 Smart Infusion Pumps are vital tools for use in administering a broad range of parenteral/intravenous medications. Safe and effective use of smart infusion pumps depends upon their integration with Pump Servers, Computerized Physician Order Entry Systems, Pharmacy Information Systems, DERS/MERS Dose/Medication Error Reduction Systems( and the digital ...
arxiv
CSF Tau Is a Biomarker of Hippocampal Injury in Cryptogenic New‐Onset Refractory Status Epilepticus
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of status epilepticus with unclear etiology. The identification of relevant early biomarkers in cNORSE is important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes in cNORSE.
Yihui Goh +8 more
wiley +1 more source
Peripheral venous catheter‐related phlebitis: A meta‐analysis of topical treatment
Nursing Open, 2023 Aim To systematically evaluate the efficacy of different topical treatments for PVC‐related phlebitis in hospital in‐patients. Design A systematic review and meta‐analysis.
Judith Garcia‐Expósito +5 more
doaj +1 more source
Substantial drag reduction in turbulent flow using liquid-infused surfaces [PDF]
, 2017 Experiments are presented that demonstrate how liquid-infused surfaces can reduce turbulent drag significantly in Taylor-Couette flow. The test liquid was water, and the test surface was composed of square microscopic grooves measuring 100 $\mu$m to 800 $\mu$m, filled with alkane liquids with viscosities from 0.3 to 1.4 times that of water.
arxiv +1 more source