Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
Advanced Healthcare Materials, EarlyView.This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Incidental MRI Findings of Acute Gadolinium Hypersensitivity
Case Reports in Neurology, 2012 A 13-year-old girl with a remote history of juvenile pilocytic astrocytoma developed acute onset flushing, tachycardia and shortness of breath immediately following administration of gadopentetate dimeglumine during routine brain MRI that subsided ...
C. Amene +3 more
doaj +1 more source
Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model
Advanced Healthcare Materials, EarlyView.A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark +9 more
wiley +1 more source
Midazolam Efficacy Against Acute Hydrogen Sulfide-Induced Mortality and Neurotoxicity. [PDF]
, 2018 Hydrogen sulfide (H2S) is a colorless, highly neurotoxic gas. It is not only an occupational and environmental hazard but also of concern to the Department of Homeland Security for potential nefarious use. Acute high-dose H2S exposure causes death, while
Anantharam, Poojya +6 more
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Advanced Healthcare Materials, EarlyView.A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li +8 more
wiley +1 more source
Studies on reticuloendothelial system and hemato-poiesis, III. Relationship between differentiation of erythroblast and oxygen tension [PDF]
, 1965 For the purpose to clarify the control mechanism of erythroid cell differentiation, the author observed morphologic changes in bone-marrow cells and circulating red cells in phenylhydrazine anemia of rabbits by introducing a mass of red cells into vein ...
Matsuoka, Kenichi
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Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions
Advanced Healthcare Materials, EarlyView.A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang +12 more
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Ralstonia mannitolilytica Bacteremia Stemming From Frequent Outpatient Intravenous Injections at a Local Clinic. [PDF]
Cureus, 2023 Kano Y, Kikuchi K.
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Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun +9 more
wiley +1 more source
In vivo tumor ultrasound-switchable fluorescence imaging via intravenous injections of size-controlled thermosensitive nanoparticles. [PDF]
Nano Res, 2023 Ren L, Liu Y, Yao T, Nguyen KT, Yuan B.
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