Results 101 to 110 of about 481,852 (304)

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

In vivo tumor ultrasound-switchable fluorescence imaging via intravenous injections of size-controlled thermosensitive nanoparticles. [PDF]

Nano Res, 2023
Ren L, Liu Y, Yao T, Nguyen KT, Yuan B.
europepmc   +1 more source

A "SCHREIBER" ADAPTER FOR INTRAVENOUS INJECTIONS [PDF]

JAMA: The Journal of the American Medical Association, 1918
Those who appreciate the good qualities of the Schreiber needle in meeting the difficulties of intravenous injection technic will appreciate the serviceability of the device here illustrated, which has been in use in my service for several months. The Schreiber needle is made in only one, or at most two sizes.
openaire   +2 more sources

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

Biodistribution of Intratracheal, Intranasal, and Intravenous Injections of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles in a Mouse Model for Drug Delivery Studies. [PDF]

Pharmaceutics, 2023
Tolomeo AM, Zuccolotto G, Malvicini R, De Lazzari G, Penna A, Franco C, Caicci F, Magarotto F, Quarta S, Pozzobon M, Rosato A, Muraca M, Collino F.   +12 more
europepmc   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

Advanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang, Qiang Chen, Aihua Jin, Xiaoqi Yang, Hui Zhou, Weiquan Gong, Jin Cheng, Jun Dai, Minjin Wang, Meihua Piao, Yuanyi Wang, Nan Zhou   +11 more
wiley   +1 more source

INTRAVENOUS INJECTIONS [PDF]

Journal of Clinical Investigation, 1932
Alfred Blalock, J. W. Beard, Charles Thuss   +2 more
openaire   +3 more sources

The use of Ultrasound in distinguishing complications of the Jugular Vein arising from Intravenous Catheters and Injections in Horses

, 2007
The ultrasound technique was used to provide both structural and functional information concerning the integrity of the jugular vein following intravenous infusion and injections.
D O Kihurani, Kihurani, D O, G Schusser, Schusser, G   +3 more
core   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

Effect of Intravenous Blood Thromboplastin Intermediates on Clotting in Rats

, 1958
Rats were given intravenous injections of blood thromboplastin intermediates. Fully formed blood thromboplastin and product II of Bergsagel and Hougie produced the defibrination syndrome, whereas thromboplastin generation reagents singly or in ...
Mona Kropatkin, Theodore H. Spaet
core   +1 more source