Results 241 to 250 of about 2,150,754 (399)

MEASUREMENT OF GLUCOSE DISPOSAL RATES IN NORMAL AND DIABETIC HUMAN SUBJECTS AFTER REPEATED INTRAVENOUS INJECTIONS OF GLUCOSE.

open access: yesJournal of Clinical Endocrinology and Metabolism, 1964
D. Streeten   +3 more
semanticscholar   +1 more source

Sanggenol L Enhances Temozolomide Drug Sensitivity by Inhibiting Mitophagy and Inducing Apoptosis Through the Regulation of the TRIM16‐OPTN Axis in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Sanggenol L, a flavonoid from mulberry, enhances glioblastoma sensitivity to temozolomide by inhibiting mitophagy and inducing apoptosis through TRIM16‐mediated OPTN degradation. In animal studies, liposomal delivery of Sanggenol L significantly improves the efficacy of its combination with TMZ, providing new insights into glioblastoma treatment ...
Hongbo Chang   +11 more
wiley   +1 more source

Assessment of the safety of hypoxia-primed mesenchymal stem cells derived from umbilical cord and adipose tissues in animals. [PDF]

open access: yesSci Rep
Dinh NT   +9 more
europepmc   +1 more source

Effects of intracerebroventricular and intravenous injections of endothelin-1 on blood pressure and sympathetic activity in urethane-anesthetized rats.

open access: yesJournal of Cardiovascular Pharmacology, 1991
H. Takahashi   +6 more
semanticscholar   +1 more source

Deficiency of SCAMP5 Triggers Pancreatic β‐Cell Secretory Dysfunction and Apoptosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates that hyperglycemia in diabetes activates ChREBP, which epigenetically represses SCAMP5 expression in pancreatic β‐cells. This SCAMP5 deficiency impairs insulin secretion by downregulating the calcium channel CaV1.2. Furthermore, reduced SCAMP5 triggers β‐cell apoptosis by stabilizing VDAC1 and enhancing its interaction with Bax,
Yingqi Zhang   +10 more
wiley   +1 more source

Experimental induction of rheumatoid factor and joint lesions in rabbits after intravenous injections of killed bacteria.

open access: yesAnnals of the Rheumatic Diseases, 1986
A. Hanglow   +5 more
semanticscholar   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

open access: yesAdvanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou   +8 more
wiley   +1 more source

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