Results 241 to 250 of about 204,601 (303)

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo, Ziqin Liu, Zimin Song, Dong Zhang, Cong Liang, Fei Fang, Kai Lei, Lina Wang, Weikang Chen, Shunli Shen, Ming Kuang, Xiaoxing Li, Jun Yu, Shiyan Wang, Lixia Xu   +14 more
wiley   +1 more source

AML‐Targeted Metal‐Polyphenol Nanoplatform Induces Ferroptosis‐ICD Cascade for Antitumor Immunity Boosting

Advanced Science, EarlyView.
Schematic illustration of the synthesis protocol for Fe‐SH@Fn, an AML‐targeted nanoplatform engineered to co‐deliver shikonin (SH) and Fe3+, synergistically boosting antitumor immunity via ferroptosis induction and immunogenic cell death (ICD). ABSTRACT Acute myeloid leukemia (AML) remains a therapeutic challenge due to its low immunogenicity and ...
Shangqin Yang, Jingxuan Wang, Kerong Tu, Xiaobing Huang, Liangliang Lv, Mingjie Peng, Qiqi Xu, Hongmei Liu, Qiang Sun, Lulu Cai   +9 more
wiley   +1 more source

Voriconazole-resistant <i>Purpureocillium lilacinum</i> endophthalmitis in an agricultural worker: A case report. [PDF]

Med Mycol Case Rep
Xu Q, Su J, Sun Z, Yang F, Li Y.
europepmc   +1 more source

Sex and individual differences in ketamine's effects on alcohol drinking in rats. [PDF]

Alcohol Clin Exp Res (Hoboken)
Jennings SD, Yates I, Saland SK, Kabbaj M.   +3 more
europepmc   +1 more source

Management of Visual Loss Following Hyaluronic Acid Filler Injections: An Algorithm-based Approach. [PDF]

Plast Reconstr Surg Glob Open
Snozzi P, van Loghem JAJ, Nguyen H, Luft AR, Saeed P.   +4 more
europepmc   +1 more source

MiniPromoters Ple384 (TH) and Ple388 (PITX3) for targeting midbrain dopaminergic neurons in mice and monkeys. [PDF]

Sci Rep
Galvan A, Choi D, Korecki AJ, de Moura Gomes A, Fornes O, Tanimura J, Farkas RA, Lam SL, Lu G, Petkau TL, Yao A, Wasserman WW, Leavitt BR, Simpson EM, Smith Y.   +14 more
europepmc   +1 more source

Role of additional topotecan injections (plus two) in reducing recurrence rate in retinoblastoma of group D and group E patients: a retrospective study. [PDF]

BMJ Open Ophthalmol
Lin X, Zheng Z, Chen H, Qian J, Liu Q, Ma R, Xue K.   +6 more
europepmc   +1 more source