Results 51 to 60 of about 1,119,893 (198)
Renal Failure, 2023 Introduction It has been observed that intravenous iron administration may suppress endogenous production of erythropoietin (EPO). We postulate that this effect may be mediated by increased FGF-23 secretion.Aim of the study To evaluate the short-term ...
Katarzyna Muras-Szwedziak +2 more
doaj +1 more source
Advanced Science, EarlyView.This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li +9 more
wiley +1 more source
Mesenchymal stem cells as cellular factories for targeted P2X7 blockade after traumatic brain injury
Neuroprotection, EarlyView.This manuscript presents a novel therapeutic strategy using mesenchymal stem cells (MSCs) engineered as living drug factories to deliver a P2X7‐blocking nanobody for treatment of ischemic stroke. By combining targeted cellular delivery with sustained local immunomodulation, the approach aims to overcome key limitations of systemic biologic ...
Lucia Fadon‐Padilla +8 more
wiley +1 more source
Weekly low-dose treatment with intravenous iron sucrose maintains iron status and decreases epoetin requirement in iron-replete haemodialysis patients [PDF]
, 2006 Background. Haemodialysis patients need sustained treatment with intravenous iron because iron deficiency limits the efficacy of recombinant human epoetin therapy in these patients.
Schiesser, Daniela +8 more
core +1 more source
Advances in research on layered double hydroxides for biomedical applications
Smart Molecules, EarlyView.Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang +13 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2017 Objective To compare the efficacy and safety of different modes of maintenance iron supplementation in dialysis patients whose renal anemia were combated,in order to find a better strategy of maintenance iron supplementation.
WU Yan-ping, WANG Xiao-qin
doaj
Hypophosphataemia in adults: approach to diagnosis and management
Internal Medicine Journal, EarlyView.Abstract Hypophosphataemia is a common electrolyte disorder which can have clinically significant consequences for bone, muscle, neurological and haematological function. Its causes range from transient transcellular shifts in hospitalised patients to chronic renal phosphate‐wasting disorders mediated by fibroblast growth factor 23 (FGF23).
Kajanan Parameshwaran +2 more
wiley +1 more source
Efficacy, tolerability and safety of intravenous iron sucrose in postpartum anaemia [PDF]
, 2019 Background: Anemia is one of major contributing factor in maternal mortality and morbidity in third world countries and according to the WHO, contributes to 40% maternal deaths.
Rajput, Rucha +4 more
core +2 more sources
Periodontitis and metabolic dysfunction‐associated steatotic liver disease
Periodontology 2000, EarlyView.Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon +6 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 6, November 2026.ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan +3 more
wiley +1 more source