Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo +17 more
wiley +1 more source
Intravenous regional anesthesia as an anesthetic technique for a patient with ventricular bigeminy.
Eapen S +3 more
europepmc +1 more source
STUDY OF INJECTION TRAMADOL AS ADDITIVE IN INTRAVENOUS REGIONAL ANESTHESIA
Rajesh Subhedar +4 more
openalex +1 more source
Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang +4 more
wiley +1 more source
Risk Factors for Intolerable Postoperative Pain After Vitreoretinal Surgery Under AoA-Guided General Anesthesia with Intravenous COX-3 Inhibitors: A Post Hoc Analysis. [PDF]
Stasiowski MJ +3 more
europepmc +1 more source
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour +14 more
wiley +1 more source
Adequacy of Anesthesia Guidance Combined with Peribulbar Blocks Shows Potential Benefit in High-Risk PONV Patients Undergoing Vitreoretinal Surgeries. [PDF]
Majer D +4 more
europepmc +1 more source
Thoracic epidural anaesthesia impairs the hemodynamic response to acute pulmonary hypertension by depressing right ventricular contractility in pigs [PDF]
Claus, P +3 more
core +1 more source
A high‐resolution intravital imaging platform combining functional ultrasound and localization microscopy enables longitudinal, minimally invasive assessment of cerebrovascular function in aging studies. The present investigation reveals aging‐related reductions in neurovascular coupling, arteriole‐to‐venule ratio and vascular density, introducing a ...
Sharon Negri +16 more
wiley +1 more source
One Dose Versus Two Doses of Intravenous Tranexamic Acid in Revision Total Joint Arthroplasty. [PDF]
Grayson W +4 more
europepmc +1 more source

