Results 261 to 270 of about 61,901 (332)

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

Advanced Science, Volume 13, Issue 1, 5 January 2026.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu, Peng Qu, Jiao Shi, Tingting Liang, Yao Gu, Xue Li, Cui Ma, Danyang Zhao, Feila Liu, Qi Liang, Panke Cheng, Qian Lei   +11 more
wiley   +1 more source

Carbon Monoxide Nanomodulator Reverses Ischemia‐Reperfusion Injury in Stroke: A Novel Dual‐Channel Therapy Mode of Co‐driving Neuroprotection and Neurogenesis

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This work develops a biomimetic and reactive oxygen species‐activated carbon monoxide (CO) nanogenerator to penetrate blood‐brain barrier, arrive in stroke‐affected regions, and release CO in a controlled manner for an innovative dual‐channel therapy strategy via co‐driving neuroprotection and neurogenesis.
Xuegang Niu, Bin Gao, Hongyi Huang, Zesheng Li, Yibin Zhang, Quanlei Liu, Chao Zhang, Yang Dai, Jinkun Xu, Mingshan Liu, Yuanyuan Zhang, Yihe Wang, Penghu Wei, Yuanxiang Lin, Yongzhi Shan, Yumin Luo, Dezhi Kang, Guoguang Zhao   +17 more
wiley   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Volume 78, Issue 1, Page 12-25, January 2026.
Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y. C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Erector Spinae Plane Block With Liposomal Bupivacaine for Cervical Spine Surgery. [PDF]

Case Rep Anesthesiol
Peterson H, Nassr A, Kerfeld M.
europepmc   +1 more source

Laparoscopic En‐Bloc Excision of Urachal Sinus With Umbilical Ligament Complex in a Pediatric Patient: A Case Report and Review of Literature

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Laparoscopic en‐bloc excision of an infected umbilical‐urachal sinus in a 12‐year‐old child. The graphical abstract summarizes key intraoperative steps, including anatomical identification, adhesiolysis, and complete excision of the urachal remnant up to its bladder attachment.
Sumeet Karna
wiley   +1 more source

The Analgesic Effects of a Saddle Block with Intrathecal Morphine for Penile-Inversion Vaginoplasty: A Retrospective Study. [PDF]

Local Reg Anesth
Girón-Arango L, Kirkham KR, Millman AL, Krakowsky Y, Wilk Goldsher Y, Drodge O, Li Q, Huszti E, Brull R.   +8 more
europepmc   +1 more source

Maxillofacial Squamous Cell Carcinoma With Cervical Metastasis and Tuberculous Lymphadenitis: Diagnostic Dilemmas and Clinical Insights

Cancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Maxillofacial squamous cell carcinoma (SCC) typically metastasizes to lymph nodes, yet coexisting tuberculous lymphadenitis is extraordinarily rare, posing diagnostic challenges. Case A 68‐year‐old female with right maxillofacial SCC and ipsilateral lymphadenopathy underwent radical resection and selective neck dissection after ...
Xierzhati Tuerxun, Meiheriban Tuerhong, Zainure Wubulihasimu, Baihetiyaer Yimin, Maimaitituxun Tuerdi, Kai Liu   +5 more
wiley   +1 more source

Anesthesia-related factors in the pathogenesis of postoperative cognitive dysfunction: a mechanistic perspective. [PDF]

Front Neurol
Qin MN, Deng YN.
europepmc   +1 more source

Impact of Anesthesia With Propofol on Epileptic Discharges Recorded by Stereo‐Electroencephalography in Pediatric Epilepsy Surgery

CNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
The number of spikes decreased under anesthesia, particularly within the SOZ, while HFOs increased under anesthesia. However, the extent of the increase did not differ between the SOZ and NSOZ. The number of HFOs appeared to be a more reliable interictal biomarker in ioEEG, particularly in the frontal cortex and cingulate cortex, and was not influenced
Chang Liu, Ping Ding, Tong Zhao, Tinghong Liu, Shijie Wu, Yuxiang Yan, Liu Yuan, Liwei Zhang, Shuli Liang   +8 more
wiley   +1 more source