Results 191 to 200 of about 51,926 (267)

Maternal substance use disorder and neonatal health: epidemiologic and socioeconomic determinants in a case-control study, Shiraz, Iran. [PDF]

BMC Pregnancy Childbirth
Oboodi R, Barzegar H, Doostfatemeh M, Bahrami R, Zolfaghari S, Salehi A.   +5 more
europepmc   +1 more source

Needle Exchange Programs and HIV Prevention: The Greater Good or the Promotion of Evil? [PDF]

, 2001
Clark, Peter A.
core   +1 more source

Effects of Intravenous Ketamine on Posttraumatic Stress Disorder (PTSD): A Systematic Review

Acta Psychiatrica Scandinavica, Volume 153, Issue 2, Page 95-107, February 2026.
ABSTRACT Introduction Posttraumatic stress disorder (PTSD) is a mental disorder resulting from exposure to traumatic events. Evidence suggests that ketamine may be efficacious in treating PTSD, however, ketamine's mechanisms in treating PTSD remain unclear. Herein, this review aims to evaluate the clinical outcomes of ketamine treatment in persons with
Liyang Yin, Andy Lu, Gia Han Le, Christine E. Dri, Sabrina Wong, Kayla M. Teopiz, Heidi Xu, Roger Ho, Taeho Greg Rhee, Heidi Ka Ying Lo, Maria‐Christina Sioufi, Yang Jing Zheng, Hezekiah C. T. Au, Hernan F. Guillen‐Burgos, Bing Cao, Roger S. McIntyre   +15 more
wiley   +1 more source

Cocaine seeking and consumption are oppositely regulated by mesolimbic dopamine in male rats. [PDF]

Nat Commun
Burgeno LM, Farero RD, Murray NL, Panayi MC, Steger JS, Soden ME, Evans SB, Sandberg SG, Willuhn I, Zweifel LS, Phillips PEM.   +10 more
europepmc   +1 more source

Trans‐Tissue Effects of Hippocampus‐ and Blood‐Derived DNA Methylation Risk Scores on Bipolar Disorder Diagnosis

Bipolar Disorders, Volume 28, Issue 1, February 2026.
ABSTRACT Objectives Bipolar disorder (BD) is a common psychiatric disorder with complex genetic and epigenetic underpinnings. This study aimed to investigate whether methylation risk scores (MRSs) derived from epigenome‐wide association studies (EWASs) for BD risk in living peripheral blood and postmortem hippocampal tissues are associated with BD ...
Kazutaka Ohi, Daisuke Fujikane, Kentaro Takai, Ayumi Kuramitsu, Yukimasa Muto, Shunsuke Sugiyama, Toshiki Shioiri   +6 more
wiley   +1 more source

Drug-Induced Epigenetic Alterations: A Set of Forensic Toxicological Fingerprints?-A Systematic Review. [PDF]

Genes (Basel)
Grassi S, Costantino A, Dimitrova A, Croce EB, Iasi F, Puggioni A, De Micco F, Vaiano F.   +7 more
europepmc   +1 more source

Troriluzole attenuates opioid intake, reinforcing efficacy, seeking behaviours, physical dependence and antinociceptive tolerance in rats

British Journal of Pharmacology, Volume 183, Issue 3, Page 505-519, February 2026.
Background and Purpose Riluzole, approved for amyotrophic lateral sclerosis (ALS), has a glutamate‐modulating profile favourable for mitigating opioid addiction. It reduces neuronal glutamate release and enhances glutamate reuptake, offering advantages over agents that only increase glutamate reuptake.
Ewa Galaj, Saadet Inan, Guo‐Hua Bi, Sonita Wiah, George Adamson, Allen B. Reitz, Zheng‐Xiong Xi, Scott M. Rawls   +7 more
wiley   +1 more source

Steroid-Induced Hyperglycaemia in a Patient With Possible Body Dissatisfaction: A Case Report. [PDF]

Cureus
Ohakpougwu CE, Bebobru WM, Labram E.
europepmc   +1 more source

The Effect of Ecopipam on the Pharmacokinetics of Concomitant Medications

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Ecopipam is a first‐in‐class dopamine D1 receptor antagonist under investigation for the treatment of Tourette syndrome. This open‐label, fixed‐sequence, three‐cohort study evaluated whether ecopipam induces or inhibits cytochrome P450 (CYP) 1A2, CYP2B6, CYP2C19, CYP2D6, CYP3A4, organic anion‐transporting polypeptide (OATP) 1B1, and p ...
Virginia D. Schmith, Danielle Graden, Lauren L. R. Lohmer, Joy Schleyer, Stephen P. Wanaski   +4 more
wiley   +1 more source

The Selective Bromodomain and Extra-Terminal Domain (BET) Inhibitor RVX-208 Reduces Cocaine-Seeking Behaviour and Alters Proteomic Pathways in the Nucleus Accumbens. [PDF]

Addict Biol
Sacko TJ, Seyednejad A, Engelhardt J, Sartor GC.   +3 more
europepmc   +1 more source