Results 151 to 160 of about 29,812 (199)
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Intravenous thrombolysis in Sneddon’s syndrome
Journal of Clinical Neuroscience, 2012Sneddon's syndrome (SS) is an uncommon disorder, characterized by the association of ischemic stroke and widespread livedo reticularis. The treatment options for SS to prevent stroke recurrence and future disability include antiplatelet therapy, anticoagulation, or immunosuppression.
Jianzhong, Sun +5 more
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Intravenous thrombolysis for acute stroke
Neurology, 1997Until recently there was no specific therapy for stroke, but the recent publication of the National Institute of Neurological Disorders and Stroke(NINDS) t-PA for Acute Stroke Trial presents the first effective, specific therapy for stroke.1 In considering whether to apply thrombolysis to any given patient, the physician must consider the factors ...
P D, Lyden +5 more
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Intravenous Thrombolysis in Acute Myocardial Infarction
Chest, 2001(CHEST 2001; 119:253S‐277S) F ibrinolytic therapy for acute myocardial infarction (MI) has been one of the most potent treatments ever developed for a condition that kills more patients worldwide than any other. This review will focus on approved agents and the randomized trials that have led to their widespread use.
Ohman E. +5 more
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Intravenous Thrombolysis for Acute Ischemic Stroke
Continuum, 2023This article reviews the history of IV thrombolysis, its current indications and implementation, the duality of the "time is brain" versus "tissue clock" approaches, the impact of endovascular thrombectomy on IV thrombolysis, the emergence of tenecteplase, and future research directions.The growing use of factor Xa inhibitors has increasingly caused ...
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Coronary Thrombolysis with Intravenous Streptokinase
Cardiology Clinics, 1987Coronary thrombolysis can be achieved with several lytic agents administered via the intravenous or intracoronary routes. Streptokinase, when administered intravenously, produces coronary thrombolysis in from 34 to 75 per cent of patients. Intravenous administration has the advantage of rapid administration without the risks or delays inherent in the ...
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2010
This chapter will review the basic mechanisms of clot formation (thrombosis) and dissolution (thrombolysis or fibrinolysis), the mechanisms of the major drug classes used in the treatment, and the results from major clinical trials. This chapter will also present evidence-based recommendations and protocols for applying thrombolytic therapy to ...
Raul Nogueira, Lee H. Schwamm
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This chapter will review the basic mechanisms of clot formation (thrombosis) and dissolution (thrombolysis or fibrinolysis), the mechanisms of the major drug classes used in the treatment, and the results from major clinical trials. This chapter will also present evidence-based recommendations and protocols for applying thrombolytic therapy to ...
Raul Nogueira, Lee H. Schwamm
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Intravenous thrombolysis for stroke
BMJ, 2010Elderly patients should not be excluded solely on the basis of age Intravenous thrombolytic treatment for acute ischaemic stroke is controversial in patients over 80 years, mainly because they have been excluded from or under-represented in the large scale randomised controlled trials of such treatment.1 2 3 In the linked study (doi:10.1136/bmj.c6046),
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Off‐label intravenous thrombolysis in acute stroke
European Journal of Neurology, 2011Background and purpose: Therapy for stroke with intravenous tissue plasminogen activator (IV‐tPA) is hampered by tight licensing restrictions; some of them have been discussed in recent literature. We assessed the safety and effectiveness of off‐label IV‐tPA in the clinical settings.Methods: Retrospective analysis of all the patients treated with IV ...
M, Guillan +9 more
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Intravenous Thrombolysis and Coronary Revascularization Rates
JAMA: The Journal of the American Medical Association, 1991To the Editor.— The impact of intravenous thrombolysis on the rates of short-term interventional procedures (cardiac catheterization, angioplasty, and bypass surgery) was addressed recently by Naylor and Jaglal 1 and, in an accompanying editorial, by Schlant.
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Intravenous Thrombolysis for Stroke Patients with G6PD Deficiency
Journal of Stroke and Cerebrovascular Diseases, 2018No reports regarding the safety of thrombolysis in acute stroke patients with a G6PD deficiency have been published to date. Here we aimed to evaluate the safety of intravenous thrombolysis for G6PD-deficient stroke patients.We enrolled each patient with acute ischemic stroke who arrived in our stroke unit within the therapeutic window and received ...
Xiaoyan, Wu +7 more
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