Results 41 to 50 of about 131,791 (361)

Pre-retinal delivery of recombinant adeno-associated virus vector significantly improves retinal transduction efficiency

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
Intravitreal injection is the most widely used injection technique for ocular gene delivery. However, vector diffusion is attenuated by physical barriers and neutralizing antibodies in the vitreous.
Hanmeng Zhang   +4 more
doaj   +1 more source

Adverse events associated with intraocular injection of anti-VEGF(bevacizumab) in retinal vein ccclusion: a case report [PDF]

open access: yes, 2015
Introduction: Antiangiogenic agents are often administered for treatment of Branch Retinal Vein Occlusion (BRVO). Among them, Bevacizumab has noticeable antiangiogenic and antiedemigenic properties and possesses great capacity to penetrate the retinal ...
ARTICO, Marco   +7 more
core   +1 more source

Awareness, knowledge, and practice: A survey of glaucoma in north Indian rural residents

open access: yesIndian Journal of Ophthalmology, 2014
Background: Studies done on the prevalence of glaucoma have reported a high proportion of undiagnosed patients. Late diagnosis is related to increased risk of glaucoma associated with visual disability.
Parveen Rewri, Mukesh Kakkar
doaj   +1 more source

Comparative lipid profiling dataset of the inflammation-induced optic nerve regeneration. [PDF]

open access: yes, 2019
In adult mammals, retinal ganglion cells (RGCs) fail to regenerate following damage. As a result, RGCs die after acute injury and in progressive degenerative diseases such as glaucoma; this can lead to permanent vision loss and, eventually, blindness ...
Bhattacharya, Sanjoy K   +5 more
core   +1 more source

Intravitreal Dexamethasone Effect on Intravitreal Vancomycin Elimination in Endophthalmitis [PDF]

open access: yesArchives of Ophthalmology, 1999
To determine whether intravitreal dexamethasone administration can alter the elimination of intravitreal vancomycin hydrochloride in rabbit eyes with experimental Streptococcus pneumoniae endophthalmitis.Albino rabbits were infected with an intravitreal inoculum of S pneumoniae (2 x 10(3) colony-forming units) and randomized after 24 hours to treatment
S S, Park   +5 more
openaire   +2 more sources

Intravitreal Dexamethasone Implant in the Treatment of Refractory Uveitic Macular Edema: A Case Report

open access: yesDelhi Journal of Ophthalmology, 2016
Macular edema is the most common cause of vision loss in uveitis. It can respond to systemic or local steroids administered as either subtenon depot or intravitreal injection.
Anisha Seth   +3 more
doaj   +1 more source

Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]

open access: yes, 2019
The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto   +5 more
core   +1 more source

SYSTEMIC PHARMACOKINETICS AND PHARMACODYNAMICS OF INTRAVITREAL AFLIBERCEPT, BEVACIZUMAB, AND RANIBIZUMAB

open access: yesRetina, 2017
Purpose: To evaluate the systemic pharmacokinetics (PKs) of aflibercept, bevacizumab, and ranibizumab in patients with neovascular age-related macular degeneration (AMD), diabetic macular edema (DME), or retinal vein occlusion (RVO). Methods: Prospective,
R. Avery   +12 more
semanticscholar   +1 more source

Systematic review: non-adherence and non-persistence in intravitreal treatment

open access: yesGraefe's Archive for Clinical and Experimental Ophthalmology, 2020
Intravitreal injection of VEGF inhibitors has become the standard of care for different macular diseases within the last years resulting in improved visual outcomes.
C. Ehlken   +6 more
semanticscholar   +1 more source

Is being female a risk factor for shallow anterior chamber? The associations between anterior chamber depth and age, sex, and body height

open access: yesIndian Journal of Ophthalmology, 2014
Aim of Study: To analyze the association between anterior chamber depth (ACD) and age, sex, and body height (BH). Materials and Methods: One thousand four hundred eighty eyes of 1480 adults 40 years of age and older receiving preoperative evaluation for ...
Wei-Cherng Hsu   +2 more
doaj   +1 more source

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