Results 111 to 120 of about 8,419,741 (275)

Intrinsic functional brain networks in health and disease [PDF]

, 2012
6 Introduction   6  6.1   Imaging  cognitive  processes  with  functional  magnetic  resonance  imaging   7  6.2   Imaging  the  brain’s  resting  state   8  6.3   Intrinsic  connectivity  networks  in  the
Riedl, Valentin, Dr. Med Valentin Riedl
core  

Brain connectivity and visual attention.

, 2023
Emerging hypotheses suggest that efficient cognitive functioning requires the integration of separate, but interconnected cortical networks in the brain. Although task-related measures of brain activity suggest that a frontoparietal network is associated
Madden, David J, Parks, Emily L
core   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Altered intrinsic regional brain spontaneous activity in patients with comitant strabismus: a resting-state functional MRI study

Neuropsychiatric Disease and Treatment, 2016
Xin Huang,1,2,* Sheng-Hong Li,3,* Fu-Qing Zhou,3 Ying Zhang,1 Yu-Lin Zhong,1 Feng-Qin Cai,3 Yi Shao,1 Xian-Jun Zeng3 1Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Jiangxi Province Clinical Ophthalmology Institute ...
Huang X, Li S, Zhou F, Zhang Y, Zhong Y, Cai F, Shao Y, Zeng X   +7 more
doaj  

Intrinsic brain activity of cognitively normal older persons resembles more that of patients both with and at-risk for Alzheimer's disease than that of healthy younger persons. [PDF]

, 2014
In Alzheimer's disease (AD), recent findings suggest that amyloid-ß-pathology (Aß) might start 20-30 years before first cognitive symptoms arise.
Plant, C., Förstl, H., Zimmer, C., Riedl, V., Zherdin, Andrew, Ortner, Marion, Kurz, Alexander, Sorg, Christian, Sorg, C., Pasquini, Lorenzo, Zherdin, A., Zimmer, Claus, Tonch, Annika, Ortner, M., Pasquini, L., Grimmer, Timo, Plant, Claudia, Kurz, A., Grimmer, T., Wohlschäger, A., Förstl, Hans, Riedl, Valentin, Tonch, A., Wohlschäger, Afra   +23 more
core   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Music and the brain: disorders of musical listening [PDF]

, 2006
The study of the brain bases for normal musical listening has advanced greatly in the last 30 years. The evidence from basic and clinical neuroscience suggests that listening to music involves many cognitive components with distinct brain substrates ...
Stewart, Lauren, Griffiths, Timothy D., Warren, J., Lauren Stewart, Von Kriegstein, K., Stewart, L., Katharina Von Kriegstein, Timothy D. Griffiths, Griffiths, T., Warren, Jason D., Jason D. Warren, JD, Warren, TD, Griffiths, von Kriegstein, K, Stewart, L; id_orcid   +14 more
core   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source