Results 151 to 160 of about 708,095 (300)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

The intrinsic bayes factor described by an example [PDF]

open access: yes, 1996
The Intrinsic Bayes Factor (IBF) has been recently introduced by Berger and Pericchi (1996) for automatic model selection and hypothesis testing in a Bayesian framework.
Pericchi, L. R., Presa, E., Fiteni, I.
core  

Some experiments on intrinsic factor [PDF]

open access: yesBiochemical Journal, 1960
N G, HEATLEY, M A, SHEIKH, K B, TAYLOR
openaire   +2 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

DIVALENT CATION AND PH DEPENDENCE OF RAT INTRINSIC FACTOR ACTION IN EVERTED SACS AND MUCOSAL HOMOGENATES OF RAT SMALL INTESTINE * [PDF]

open access: yes, 1961
In 1959 it was reported in these pages (1) that hog intrinsic factor concentrate enhanced the uptake of radioactive vitamin B12 (Co60-B12) by everted sacs of rat small intestine in the cold.
Victor Herbert, William B
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Satisfaction with creativity: a study of organisational characteristics and individual motivations [PDF]

open access: yes
In answering the question of what influences satisfaction for creativity in the workplace, this work takes into account the extent to which the organization supports human aspiration to creativity. The empirical model uses survey data encompassing over 4,
Silvia Sacchetti, Ermanno C. Tortia
core  

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