Results 121 to 130 of about 361,243 (290)
, 2014 Shape-from-X is an important class of problems in the fields of geometry processing, computer graphics, and vision, attempting to recover the structure of a shape from some observations. In this paper, we formulate the problem of shape-from-operator (SfO)
Boscaini, Davide +2 more
core
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
Distance-based metrics for comparing conformational ensembles of intrinsically disordered proteins [PDF]
, 2020 Tamás Lázár +5 more
openalex +1 more source
FEBS Open Bio, EarlyView.We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley +1 more source
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
FEBS Open Bio, EarlyView.Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco +5 more
wiley +1 more source
Optimizing the spatial approximation tree from the root
Journal of Computer Science and Technology, 2008 Many computational applications need to look for information in a database. Nowadays, the predominance of nonconventional databases makes the similarity search (i.e., searching elements of the database that are "similar" to a given query) becomes a ...
Alejandro J. Gómez +2 more
doaj
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Comparison of Metrics of Inter-Structure Distance When Applied to Molecular Dynamics Simulations of Intrinsically Disordered Proteins [PDF]
, 2014 Robert L. Wang +6 more
openalex +1 more source
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Analysis of network behavior characteristic and influence factor based on the peak traffic
Tongxin xuebao, 2012 Based on the burstiness of network traffic,the peak traffic metric was introduced,and the method which was used to evaluate network operation and plan capacity was proposed.The network intrinsic features and the peak traffic for the 21 CERNET campus ...
Ai-ping ZHOU, Guang CHENG
doaj +2 more sources