Results 31 to 40 of about 15,372 (214)

Research on explosion-proof technology for coal mine rescue robot

open access: yesGong-kuang zidonghua, 2019
The paper introduced general situation of explosion-proof technology of coal mine rescue robot, and summarized the research status and application of explosion-proof technology of coal mine rescue robot at home and abroad, and pointed out some progress ...
ZHENG Xuezhao   +3 more
doaj   +1 more source

Health status identification of catenary based on VMD and FA-ELM

open access: yesJournal of Algorithms & Computational Technology, 2021
Catenary works as a key part in the electric railway traction power supply system, which is exposed outdoors for a long time and the failure rate is very high. Once a failure occurs, it will directly affect the driving safety. Based on the above, a model
Lingzhi Yi   +5 more
doaj   +1 more source

Optimization Design of Intrinsic Safety Pilot Circuit for Motor Remote Start and Stop

open access: yesMeikuang Anquan, 2020
This paper introduces the types of remote starting and stopping pilot circuits of existing motors, the existence of mis-starting, the inability to identify all line faults and the unstable operation of power supply voltage reduction, and proposes an ...
ZHANG Yuxiang, SONG Jiancheng, TIAN Muqin
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Design of a type of intrinsic safety miner lamp with identification card

open access: yesGong-kuang zidonghua, 2013
In view of problems that equipments carried by underground miner increase because of individual design and power supply of identification card, and sometimes positioning would fail because that charging or change of battery of identification card are not
HUO Yin-jia, GU Yi-dong
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Supporting Solidarity

open access: yesVoices in Bioethics, 2023
Photo ID 72893750 © Rawpixelimages|Dreamstime.com ABSTRACT Solidarity is a concept increasingly employed in bioethics whose application merits further clarity and explanation.
Claire Moore   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A Single-Stage Isolated Battery Charger Using Nonbridged Positive Cuk Converter Configuration

open access: yesIET Electrical Systems in Transportation, 2023
This article presents a nonbridged isolated positive Cuk (NB-IPCuk) converter-based single-stage battery charging system (SSBCS). The architecture of the suggested charger ensures the intrinsic advantage of power quality improvement in discontinuous ...
Tanmay Shukla   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy