Results 41 to 50 of about 574,120 (263)
Frontiers in Energy Research, 2021 Nuclear reactor modeling has been shifting, over the last decades, towards full-core multiphysics analysis due to the ever-increasing safety requirements and complexity of the designs of innovative systems.
Andrea Di Ronco +5 more
doaj +1 more source
Atomic Spectral Features During Thermonuclear Flashes on Neutron Stars [PDF]
, 2003 The gravitational redshift measured by Cottam, Paerels and Mendez for the neutron star (NS) in the low-mass X-ray binary EXO 0748-676 depends on the identification of an absorption line during a type I burst as the H$\alpha$ line from hydrogenic Fe.
Day C. S. R. +14 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Linagliptin–-A Novel Dipeptidyl Peptidase Inhibitor for Type 2 Diabetes Therapy
Clinical Medicine Insights: Endocrinology and Diabetes, 2012 Incretin based therapies have been introduced into the treatment options of type 2 diabetes a few years ago. Among them, the orally active DPP-4 inhibitors have established themselves as insulinotropic agents.
Baptist Gallwitz
doaj +1 more source
Testing of low-current equipment in explosive atmospheres [PDF]
MATEC Web of ConferencesAll activities involving flammable substances capable of generating an atmosphere mixed with air, in the form of gases, vapors, flammable fog, or dust may involve a danger of explosion.
Beldiman Alexandru Marian +1 more
doaj +1 more source
Consumer attitudes and preference exploration towards fresh-cut salads using best–worst scaling and latent class analysis [PDF]
, 2019 This research explored the preferences and buying habits of a sample of 620 consumers of fresh-cut, ready-to-eat salads. A best–worst scaling approach was used to measure the level of preference stated by individuals regarding 12 attributes for quality ...
Bargetto A. +5 more
core +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Kinetic research on heterogeneously catalysed processes: a questionnaire on the state-of-the-art in industry [PDF]
, 1997 On the initiative of the Working Party `Chemical Engineering in the Applications of Catalysis¿ of the European Federation of Chemical Engineering an assessment of the issues in the determination and application of kinetic data within the European ...
Bos, A.N.R. +3 more
core +4 more sources
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source