Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Who pollinates exotic plants? A global assessment across native and exotic ranges
Global Ecology and ConservationThe spread of exotic plant species is a global issue with substantial ecological and economic costs. One factor that can contribute to their capacity to establish and spread beyond their native range is their ability to attract novel pollinators (i.e ...
Natthaphong Chitchak +3 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Back in Europe: Quamtana spiders (Araneae: Pholcidae) in Germany
Arachnologische Mitteilungen, 2015 Two undescribed species of the African pholcid spider genus Quamtana have been found in German greenhouses and plant markets since 2012. Both species seem to have established stable populations.
Huber, Bernhard +4 more
doaj +1 more source
Evaluation of Microbiological Preparations’ Effect on the Propagation of Introduced Species of Trees [PDF]
, 2020 Ekaterina Gorb, G V Barayshchuk
openalex +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
First record of the jumping spider Icius subinermis (Araneae, Salticidae) in Hungary
Arachnologische Mitteilungen, 2017 We report the first record of Icius subinermis Simon, 1937, one female, from Budapest, Hungary. We provide photographs of the habitus and of the copulatory organ.
Korányi, Dávid +2 more
doaj +1 more source
First record of Darcya vandellioides (Benth.) Scatigna (Plantaginaceae) in the Brazilian Amazon and first report of hydathodes in the Gratioleae [PDF]
Acta Botânica BrasílicaDarcya vandellioides was originally endemic to the Brazilian Atlantic Forest, and it is herein recorded for the first time in the Amazon domain in Mato Grosso, Brazil.
Ana Kelly Koch +5 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source