Results 61 to 70 of about 1,829,683 (354)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The same vectors that introduce species to new ranges could move them among native populations, but how human‐mediated dispersal impacts native ranges has been difficult to address because human‐mediated dispersal and natural dispersal can simultaneously
Anthony L. Einfeldt +2 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Introducing the biogeographic species pool
The species pool concept has played a central role in the development of ecological theory for at least 60 yr. Surprisingly, there is little consensus as to how one should define the species pool, and consequently, no systematic approach exists. Because the definition of the species pool is essential to infer the processes that shape ecological ...
Carstensen, Daniel Wisbech +4 more
openaire +2 more sources
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
A New \u3ci\u3eEutarsopolipus\u3c/i\u3e (Acari: Podapolipidae); Parasite of \u3ci\u3eHarpalus Herbivagus\u3c/i\u3e (Coleoptera: Carabidae) From Michigan [PDF]
Eutarsopolipus porteri n. sp. (Acari: Podapolipidae) is described from HarpaIus herbivagus and E. elongatus is reported for the first time in North America from Amara aenea (Coleoptera: Carabidae) from Fort Custer State Recreation Area, Kalamazoo County,
Husband, Robert W
core +2 more sources
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Invasive plant species in the forest parks of Yekaterinburg [PDF]
Invasive species-introduced species, spontaneously settled outside their natural range, and successfully adapted to the new growing conditions. The problem of invasive species penetration, both herbaceous and woody, has long been a concern of scientists,
Luganskaya, S. N. +2 more
core
Alien plants in urban nature reserves : from red-list species to future invaders? [PDF]
Urban reserves, like other protected areas, aim to preserve species richness but conservation efforts in these protected areas are complicated by high proportions of alien species.
Jarošík, Vojtěch +2 more
core +2 more sources
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source

