Results 91 to 100 of about 2,292,613 (306)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Conservation, Society and Invasive Species [PDF]
, 2011 Invasive species pose a major environmental threat, and are frequently the subject of biodiversity conservation programmes. As stakeholder and public concerns surrounding invasive species have become increasingly recognised and better articulated ...
Ford-Thompson, Adriana E S +1 more
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Some features of rare and endangered plant species introduction
BIO Web of Conferences, 2019 The article discusses the features and main stages of rare and endangered plant species introduction. It is necessary to be guided by the principles of priority and expediency in the preparatory stage, which includes the analysis of literary data and ...
Elisafenko Tatyana, Dorogina Olga
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Introduction of wild MAP species into the field culture
Julius-Kühn-Archiv, 2016 Althea officinalis L., Dracocephalum moldavica L., Gentiana lutea L., Rhodiola rosea L., and Valeriana officinalis L. are the species of wild medicinal plants which are not very commonly grown in field culture.
Dušková, Elena +3 more
doaj +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Detectability in audio-visual surveys of tropical rainforest birds : the influence of species, weather and habitat characteristics [PDF]
, 2015 This research was funded by the Australian Government’s National Environmental Research Program, the Stuart Leslie Bird Research Award from Birds Australia (http://www.birdsaustralia.com.au/), the Earthwatch Institute (http://www.earthwatch.org/australia/
Shoo, Luke P. +11 more
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Інтродукція Рослин, 2018 Objective – to study the species composition and the state of introducing populations of plants of Caucasian flora on the botanical and geographic plant Caucasus of M.M. Gryshko National Botanical Garden of the NAS of Uk raine (NBG).
S.Ya. Didenko
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source