Results 111 to 120 of about 35,704 (267)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Kerr binary dynamics from minimal coupling and double copy
Journal of High Energy PhysicsWe construct a new Yang-Mills Lagrangian based on a notion of minimal coupling that incorporates classical spin effects. The construction relies on the introduction of a new covariant derivative, which we name “classical spin covariant derivative”, that ...
Francesco Alessio
doaj +1 more source
Introduction to Renormalization Theory and Chiral Gauge Theories in Dimensional Regularization with Non-Anticommuting $γ_5$ [PDF]
, 2023 Hermès Bélusca-Maïto +5 more
openalex +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
The cosmological constant, dark matter and the electroweak scale meet in the Swampland
Journal of High Energy PhysicsThe Swampland program, which looks for low energy theories consistent with quantum gravity, has led to the introduction of a dark dimension stemming from the cosmological constant.
Kazem Bitaghsir Fadafan +1 more
doaj +1 more source
Gauge Theories in Particle Physics: A Practical Introduction, Volume 2: Non-Abelian Gauge Theories
, 2012 I. J. R. Aitchison, Tony Hey
openalex +2 more sources
Introduction to a provisional mathematical definition of Coulomb branches of $3$-dimensional $\mathcal N=4$ gauge theories [PDF]
, 2016 Hiraku Nakajima
openalex +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source