Results 91 to 100 of about 166,319 (306)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

A machine learning approach with verification of predictions and assisted supervision for a rule-based network intrusion detection system [PDF]

open access: yes, 2008
Network security is a branch of network management in which network intrusion detection systems provide attack detection features by monitorization of traffic data.
Fernández Villamor, José Ignacio   +1 more
core   +1 more source

An Implementation of Intrusion Detection System Using Genetic Algorithm

open access: yes, 2012
Nowadays it is very important to maintain a high level security to ensure safe and trusted communication of information between various organizations. But secured data communication over internet and any other network is always under threat of intrusions
Bikas, Md. Abu Naser   +2 more
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Intrusion Detection By Data Mining Algorithms: A Review

open access: yesJournal of New Results in Science, 2013
– With the increasing use of network-based services and sensitive information on networks, maintaining information security is essential. Intrusion Detection System is a security tool used to detect unauthorized activities of a computer system or network.
Marjan Kuchaki Rafsanjani   +1 more
doaj  

IDSGAN: Generative Adversarial Networks for Attack Generation against Intrusion Detection

open access: yes, 2019
As an important tool in security, the intrusion detection system bears the responsibility of the defense to network attacks performed by malicious traffic.
Lin, Zilong, Shi, Yong, Xue, Zhi
core  

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Intrusion detection techniques of variable-frequency vector control system

open access: yes工程科学学报, 2019
As induction motors are the control core in variable-frequency speed-regulating systems, their efficient operation in industrial production processes needs to be ensured.
CAO Ce   +3 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

INTRUSION DETECTION AND PREVENTION SYSTEM IN SME'S LOCAL NETWORK BY USING SURICATA

open access: hybrid, 2023
Prakaash Veerasingam   +4 more
openalex   +2 more sources

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