Results 91 to 100 of about 19,399,754 (289)

Multi-objective optimization algorithms for intrusion detection in IoT networks: A systematic review

open access: yesInternet of Things and Cyber-Physical Systems
The significance of intrusion detection systems in networks has grown because of the digital revolution and increased operations. The intrusion detection method classifies the network traffic as threat or normal based on the data features.
Shubhkirti Sharma   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Hybrid Intrusion Detection System for Smart Home Applications

open access: yes, 2020
Smart homes, which incorporate IoT technologies to provide home security, efficient environmental services, conveniences, and improved living standards, are becoming the centre of smart urban developments.
Man Qi   +5 more
core   +1 more source

Probability Risk Identification Based Intrusion Detection System for SCADA Systems [PDF]

open access: yes, 2018
. As Supervisory Control and Data Acquisition (SCADA) systems control several critical infrastructures, they have connected to the internet. Consequently, SCADA systems face different sophisticated types of cyber adversaries.
Sitnikova, E ; https://orcid.org/   +7 more
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Distributed Hierarchical IDS For MANET Over AODV+. [PDF]

open access: yes, 2007
In this paper, we introduce background knowledge of wireless ad hoc networking mobile ad hoc network (MANET) as well as intrusion detection system (IDS) and mobile agents.
Samsudin, Azman, Pahlevanzadeh, Bahareh
core   +1 more source

Home - About - Disclaimer - Privacy