Results 121 to 130 of about 988,120 (358)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

The Development of Agent Information for Intrusion Detection

open access: yesQuery: Jurnal Sistem Informasi, 2017
As the challenges and problems surround intrusion rises rapidly, the intrusion detection system has been gradually developed. Agent-based approach for intrusion detection system has developed from single to multi agent, and later developed mobile agents ...
Bambang Sugiantoro
doaj  

Anomaly Detection pada Intrusion Detection System Menggunakan CLIQUE Partitioning [PDF]

open access: yes, 2012
ABSTRAKSI: Intrusi adalah semua tindakan yang mengancam ketersediaan, integritas, dan kerahasiaan sumber daya jaringan, seperti user account, file system, system kernel, dan sebagainya.
Nungky Nastaiinullah
core  

A Case Study on Using Deep Learning for Network Intrusion Detection [PDF]

open access: yesarXiv, 2019
Deep Learning has been very successful in many application domains. However, its usefulness in the context of network intrusion detection has not been systematically investigated. In this paper, we report a case study on using deep learning for both supervised network intrusion detection and unsupervised network anomaly detection.
arxiv  

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

Well‐being on supportive techniques in amyotrophic lateral sclerosis: from neurologists' perspective

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1874-1883, December 2022., 2022
Abstract Objective To investigate intercultural neurologists' perception of well‐being in patients with amyotrophic lateral sclerosis (ALS) using gastrostomy (PEG), non‐invasive, and/or invasive ventilation (NIV/IV) and to analyse the determinants and impact on the management of the above medical interventions (MIs).
Krzysztof Barć   +7 more
wiley   +1 more source

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