Results 41 to 50 of about 52,550 (252)
The use of gastrointestinal intubation studies for controlled release development [PDF]
British Journal of Clinical Pharmacology, 2009 WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Regional gastrointestinal absorption and toleration studies to support controlled release (CR) development have been limited to naso‐intubation and telemetric capsule methods.• The use of intubation for this purpose has been individually reported for single CR candidates; viz rivastigmine, and UK‐338,003 ...
openaire +2 more sources
National Consensus on the Use of Sedation Drugs in the Gastrointestinal Endoscopic Procedures [PDF]
, 2017 Gastrointestinal endoscopy is rapidly developing and several gastrointestinal endoscopy equipment are available for both diagnostic and therapeutic purposes.
Abdullah, M. (Murdani) +8 more
core +1 more source
TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2
Advanced Science, EarlyView.This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao +12 more
wiley +1 more source
Egyptian Journal of Critical Care Medicine, 2020 Ascaris lumbricoides is an intestinal worm that is most prevalent in tropical and subtropical regions, and is usually present with gastrointestinal symptoms in younger age group.
Hashim Mohammad +3 more
doaj +1 more source
European Journal of Case Reports in Internal Medicine, 2021 Introduction: Arterio-oesophageal fistulae are a very uncommon cause of severe gastrointestinal bleeding, and mostly result from an aberrant right subclavian artery and mediastinal surgery or prolonged endotracheal/nasogastric intubation.
Andra Glodean +4 more
doaj +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background With population aging and extended healthy life expectancy, the management of acute cholecystitis (AC) in patients aged ≥ 85 years has evolved. However, the Tokyo Guidelines 2018 (TG18) for AC provide no specific risk assessment criteria for this population.
Yuta Kobayashi +9 more
wiley +1 more source
International Journal of Medical Toxicology and Forensic Medicine, 2021 Background: Methanol poisoning is a life-threatening condition that requires accurate prognosis and treatment. This study aims to evaluate the predictive value of laboratory and clinical variables in methanol poisoning. Methods: This was an observational
Negar Rafiei Tabatabaiei +6 more
doaj
Gut and Liver, 2022 Background/Aims: Endoscopic retrograde cholangiopancreatography (ERCP) in patients with surgically altered anatomy (SAA) is challenging to gastrointestinal endoscopists.
Eunae Cho +3 more
doaj +1 more source
Annals of Gastroenterological Surgery, EarlyView.This systematic review and meta‐analysis of 38 studies, encompassing over 5000 patients, compared extralevator abdominoperineal excision (ELAPE) with standard abdominoperineal excision (APE) in patients with advanced low rectal cancer. ELAPE was associated with significantly improved overall and disease‐free survival, reduced intraoperative perforation
Sarolta Beáta Kávási +7 more
wiley +1 more source
, 2016 Cervical and high thoracic spinal cord injury (SCI) drastically impairs autonomic nervous system function. Individuals with SCI at thoracic spinal-level 5 (T5) or higher often present cardiovascular disorders that include resting systemic arterial ...
Besecker, Emily Swartz +4 more
core +1 more source