Results 71 to 80 of about 12,115 (204)

Cellular Adaptation to Mechanical Stress Emerges via Cell Shrinkage Triggered by Nonlinear Calcium Elevation

open access: yesAdvanced Science, Volume 12, Issue 38, October 13, 2025.
Here, a decision‐making mechanism underlying mechanical adaptation is demonstrated. This study demonstrates that cellular adaptation to mechanical stress can be induced by applying low‐amplitude stretch to cells. When the stretch reaches a critical amplitude threshold, it triggers Ca2⁺‐dependent positive feedback, which induces cholesterol efflux and ...
Zhengyan Wang   +21 more
wiley   +1 more source

Tracheal suctioning improves gas exchange but not hemodynamics in asphyxiated lambs with meconium aspiration. [PDF]

open access: yes, 2015
BackgroundCurrent neonatal resuscitation guidelines recommend tracheal suctioning of nonvigorous neonates born through meconium-stained amniotic fluid.MethodsWe evaluated the effect of tracheal suctioning at birth in 29 lambs with asphyxia induced by ...
Gugino, Sylvia F   +7 more
core  

Fiberoptička bronhoskopija prema video laringoskopiji u zbrinjavanju pedijatrijskog dišnog puta [PDF]

open access: yes, 2016
The primary goal of pediatric airway management is to ensure oxygenation and ventilation. Routine airway management in healthy pediatric patients is normally easy in experienced hands.
Dušanka Janjević   +2 more
core   +2 more sources

Tumor Extracellular Vesicles Aggravate Mitochondrial Damage in Myocardial Ischemia/Reperfusion Injury

open access: yesAdvanced Science, Volume 12, Issue 35, September 18, 2025.
This study reveals a novel mechanistic connection between cancer and ischemia/reperfusion (I/R)‐induced cardiac injury. The meta‐analysis demonstrates significantly higher incidence ratios of both all‐cause mortality and cardiovascular mortality in cancer patients undergoing percutaneous coronary intervention (PCI) compared to non‐cancer patients.
Zhongting Mei   +14 more
wiley   +1 more source

tRF‐5004b Enriched Secretory Autophagosomes Induce Endothelial Cell Activation to Drive Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, Volume 12, Issue 33, September 4, 2025.
Acute respiratory distress syndrome (ARDS) is a severe lung condition with limited treatments, often triggered by overactive endothelial cells (ECs). It is identified that macrophage‐derived secretory autophagosomes (MSAPs) exacerbate lung damage by activating EC function.
Xing‐xing Zhu   +17 more
wiley   +1 more source

Izazovi opstetricijske anestezije: otežana vizualizacija larinksa [PDF]

open access: yes, 2016
Obstetric anesthesia is one of the high risk subspecialties of anesthesia practice. Anesthesia related complications are the sixth leading cause of maternal mortality.
Başak Ceyda Orbey Meço   +6 more
core   +2 more sources

A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment

open access: yesAnimal Models and Experimental Medicine, Volume 8, Issue 9, Page 1717-1724, September 2025.
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng   +4 more
wiley   +1 more source

Esophageal misplacement of a single-lumen tube after its exchange for a double-lumen tube despite the use of an airway-exchange catheter

open access: yesSaudi Journal of Anaesthesia, 2013
An airway-exchange catheter (AEC) can increase the safety of exchanges of endotracheal tubes (ETTs); however, the procedure is associated with potential risks.
Sung Mi Hwang   +3 more
doaj   +1 more source

Prediction of difficult laryngoscopy / difficult intubation cases using upper airway ultrasound measurements in emergency department: a prospective observational study

open access: yesBMC Emergency Medicine, 2023
Introduction Difficult laryngoscopy and intubation are serious problems among critically ill patients in emergency department (ED) so utility of a rapid, accurate and noninvasive method for predicting of these patients are necessary.
Mehran Sotoodehnia   +5 more
doaj   +1 more source

Global Lactylome Reveals Lactylation‐Dependent Mechanisms Underlying CXC Motif Chemokine Ligand 12 Expression in Pulmonary Endothelium During Acute Respiratory Distress Syndrome

open access: yesMedComm, Volume 6, Issue 9, September 2025.
In quiescent PECs, Eno1 binds to the 3′ UTR of CXCL12 mRNA to prevent translation. Following activation, lactate is accumulated and then mediates an increase in lysine lactylation. Eno1, a substrate in this modification, releases bound CXCL12 mRNA upon lactylation to promote translation. Meanwhile, the activity of Eno1 as a glycolytic enzyme increases,
Xu Liu   +5 more
wiley   +1 more source

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