The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction
Advanced Science, EarlyView.Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang +8 more
wiley +1 more source
A bench study comparing between scalpel-bougie technique and cannula-to-Melker technique in emergency cricothyroidotomy in a porcine model [PDF]
Korean Journal of Anesthesiology, 2018 Background The ideal emergency cricothyroidotomy technique remains a topic of ongoing debate. This study aimed to compare the cannula-to-Melker technique with the scalpel-bougie technique and determine whether yearly training in cricothyroidotomy ...
See Seong Chang +4 more
doaj +1 more source
Studying continuous, time-varying, and/or complex exposures using longitudinal modified treatment policies [PDF]
arXiv, 2023 This tutorial discusses methodology for causal inference using longitudinal modified treatment policies. This method facilitates the mathematical formalization, identification, and estimation of many novel parameters, and mathematically generalizes many commonly used parameters, such as the average treatment effect.
arxiv
Predictors of Successful Decannulation Using a Tracheostomy Retainer in Patients with Prolonged Weaning and Persisting Respiratory Failure [PDF]
, 2012 Background: For percutaneously tracheostomized patients with prolonged weaning and persisting respiratory failure, the adequate time point for safe decannulation and switch to noninvasive ventilation is an important clinical issue.
Abboussouan LS +30 more
core +2 more sources
Reinforcing Stromal Cell Spheroid Through Red‐Light Preconditioning for Advanced Vascularization
Advanced Science, EarlyView.This study presents a novel approach to enhance stromal cell therapy for myocardial infarction by combining OLED‐based photobiomodulation (OPBM) preconditioning with 3D spheroid culture of hADSCs. The engineered spheroids improve angiogenesis, arterialization, and cardiac function in vivo, offering a next‐generation therapeutic strategy to overcome ...
Yu‐Jin Kim +12 more
wiley +1 more source
American Journal of Perinatology Reports, 2020 Background Endotracheal intubation is a skill required for resuscitation. Due to various reasons, intubation opportunities are decreasing for health care providers.
Iram Musharaf +2 more
doaj +1 more source
A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration [PDF]
, 2007 This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol ...
Karis Misiran,, Muhd Helmi Azmi,
core
Extracorporeal CO2 removal in hypercapnic patients who fail noni nvasive ventialtion and refuse endotracheal intubation. a case series [PDF]
, 2015 Noninvasive ventilation (NIV) represents the standard of care for patients with exacerbation of chronic obstructive pulmonary disease. However, NIV fails in almost 40% of the most severe forms of acute hypercapnic respiratory failure and patients must ...
Alessandri, F +5 more
core +1 more source
Plastic and Reconstructive Surgery - Global Open, 2018 Summary: Acquisition of a secure airway is an essential element of the operative management of maxillofacial trauma. Of the options available, submental intubation is an alternative to tracheostomy. The access should be accomplished via a midline approach rather than lateral through the mylohyoid, an armored endotracheal tube ...
Edward A. Luce, MD, Sonia M. Alvarez, MD
openaire +3 more sources
Advanced Science, EarlyView.Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang +8 more
wiley +1 more source