Results 41 to 50 of about 769,743 (291)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

The psychological-type profile of practising British druids compared with Anglican churchgoers [PDF]

open access: yes, 2012
This study employs psychological-type theory to profile practising British Druids and to compare their profile with that of Anglican churchgoers. A sample of 75 participants at a camp organised by The Order of Bards, Ovates and Druids in celebration of ...
Billington, Ursula   +3 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Hidden Context Influence on Pattern Recognition

open access: yesJournal of Telecommunications and Information Technology, 2013
The influence of hidden additional information concerning the circumstances of input data acquisition on the quality of decisions based on the data is considered. An analogue to the intuition influencing natural decision making is indicated. The problem
Juliusz L. Kulikowski
doaj   +1 more source

Does intuitive mindset influence belief in God? A registered replication of Shenhav, Rand and Greene (2012)

open access: yesJudgment and Decision Making, 2020
In 2012, two independent groups simultaneously demonstrated that intuitive mindset enhances belief in God. However, there is now some mixed evidence on both the effectiveness of manipulations used in these studies and the effect of mindset manipulation ...
S. Adil Saribay   +2 more
doaj   +1 more source

Manipulating reliance on intuition reduces risk and ambiguity aversion [PDF]

open access: yes, 2013
Prior research suggests that those who rely on intuition rather than effortful reasoning when making decisions are less averse to risk and ambiguity. The evidence is largely correlational, however, leaving open the question of the direction of causality.
Butler, Jeffrey V.   +2 more
core  

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

Cognitive conflict in social dilemmas: An analysis of response dynamics

open access: yesJudgment and Decision Making, 2014
Recently, it has been suggested that people are spontaneously inclined to cooperate in social dilemmas, whereas defection requires effortful deliberation.
Pascal J. Kieslich, Benjamin E. Hilbig
doaj   +1 more source

Proof phenomenon as a function of the phenomenology of proving [PDF]

open access: yes, 2015
Kurt Gödel wrote (1964, p. 272), after he had read Husserl, that the notion of objectivity raises a question: “the question of the objective existence of the objects of mathematical intuition (which, incidentally, is an exact replica of the question of ...
Hipólito, Inês
core   +1 more source

In the winning mood: Affect in the Iowa gambling task

open access: yesJudgment and Decision Making, 2008
The present research aimed to test the role of mood in the Iowa Gambling Task (IGT; Bechara et al., 1994). In the IGT, participants can win or lose money by picking cards from four different decks.
Marieke de Vries   +4 more
doaj   +1 more source

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