Results 91 to 100 of about 4,185 (146)

Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes

Advanced Therapeutics, Volume 9, Issue 2, February 2026.
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava, Lydia Herrmann, Eden Ozkan, Abhiram Kunamneni, Vinamra Swaroop, Geetika Nehra, Rohit Srivastava, Pratima Tripathi, Ken Inoki, Julie E. Goodwin   +9 more
wiley   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Characterization of pediatric eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis in a nationwide cohort

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 2, Page 531-540, February 2026.
Abstract Objectives Nonesophageal eosinophilic gastrointestinal disorders (non‐EoE EGIDs) are rare, underrecognized inflammatory diseases of the gastrointestinal (GI) tract, especially in children. Their clinical heterogeneity and lack of specific biomarkers contribute to diagnostic delays and therapeutic challenges.
Sara Renzo, Luca Scarallo, Selene Del Vespa, Giulia Angelino, Matteo Bramuzzo, Enrico Felici, Flavio Labriola, Francesca Laganà, Lorenzo Norsa, Salvatore Oliva, Marisa Piccirillo, Elena Pozzi, Francesca Rea, Giusy Russo, Francesco Valitutti, Giovanna Zuin, Paolo Lionetti   +16 more
wiley   +1 more source

DSM‐5 Functional Framework: Structure and Psychopathological Correlates of the DSM‐5 Levels of Functioning Questionnaire–Short Form

Personality and Mental Health, Volume 20, Issue 1, February 2026.
ABSTRACT Interest in the Level of Personality Functioning (LPF), defined by Criterion A of the Alternative Model for Personality Disorders (AMPD), is growing. LPF includes self‐functioning (identity, self‐direction) and interpersonal functioning (empathy, intimacy).
Claudio Sica, Corrado Caudek, Ilaria Colpizzi, Gioia Bottesi   +3 more
wiley   +1 more source

The Calcium‐Binding Protein S100A10 (p11) Is Required for Normal Motor Performance by Regulating Vesicle Dynamics at Excitatory Synapses

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim Identifying interactors in sensorimotor processing and neurotransmission remains a current challenge for understanding neural information processing and brain function. Methods To evaluate the role of p11 in sensorimotor processing and excitatory synaptic neurotransmission, neuron‐specific lentivirus‐directed p11 silencing, small ...
Esther Vilches‐Herrando, Guillermo Rodríguez‐Bey, Rosendo G. Hernández, Ángela Gento‐Caro, Ángel M. Pastor, Antonio Campos‐Caro, David González‐Forero, Bernardo Moreno‐López   +7 more
wiley   +1 more source

Exosomes in Hypertrophic Scars and Keloids: Mechanisms and Therapeutic Potentials—A Narrative Review

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hypertrophic scars and keloids, types of pathological scars, arise from dysregulated wound healing, marked by abnormal fibroblast activation and excessive extracellular matrix (ECM) deposition. Current treatments have high recurrence rates and side effects, necessitating targeted therapies. Exosomes, extracellular vesicles mediating
Mengke Wu, Jianfeng Zhang, Na Xiong, Yixiao Ma, Lingling Yong, Huaxu Liu, Qin Guo   +6 more
wiley   +1 more source

Expectant management of a pediatric patient with traumatic intussusception: Case report with literature review. [PDF]

Radiol Case Rep
Albalawi N, Wasili M, Alageel A, Sami D, Aldraihem K, Shabana E.   +5 more
europepmc   +1 more source

A case report of jejunal myeloid sarcoma presented with intestinal intussusception in a 19-year-old man: An uncommon presentation of a rare disease. [PDF]

Int J Surg Case Rep
Ahmadinejad M, Shakerpour A, Azarimanesh P, Mansourian B, Ahmadinejad Y, Bagherpour JZ.   +5 more
europepmc   +1 more source

A Rare Case of Ileal Intussusception Caused by Primary Small Bowel Trichobezoar and Meckel's Diverticulum in an Autistic Child. [PDF]

Clin Case Rep
Messaoud M, Joya HU, Alansari AN, Jouini A, Ksiaa A, Zrig A, Sahnoun L.   +6 more
europepmc   +1 more source

Intussusception secondary to Peutz-Jeghers syndrome: a case report and literature review of diagnostic and therapeutic advances. [PDF]

Front Med (Lausanne)
Zhang J, Xie TH, Fu Y, Jin XS, Wang Q, Niu Z.   +5 more
europepmc   +1 more source