Results 51 to 60 of about 4,185 (146)

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

Stepped-wedge randomised trial of laparoscopic ventral mesh rectopexy in adults with chronic constipation: Study protocol for a randomized controlled trial [PDF]

, 2018
BACKGROUND: Laparoscopic ventral mesh rectopexy (LVMR) is an established treatment for external full-thickness rectal prolapse. However, its clinical efficacy in patients with internal prolapse is uncertain due to the lack of high-quality evidence ...
Al-Khafaji, P, Bellamacina, C, Brown, S, Burlinson, A, Burrows, J, Cairns, L, Campbell, K, Chapman, M, Clarke, A, Collie, M, Corrigan, N, Cruickshank, N, Davies, G, Di Tanna, GL, Dixon, A, Eldridge, S, Emmanuel, A, Emmett, C, Gilbert, D, Giordano, P, Grossi, U, Hance, J, Hansen, J, Harding, J, Horrocks, E, Jayne, D, Knowles, CH, Lacy-Colson, J, Lindsey, I, Manivannan, A, Marlin, N, Mason, J, McAlees, E, McCurrach, I, McLaughlin, J, Mercer-Jones, M, Michael, K, Miller, A, Moss-Morris, R, Nisar, P, Norton, C, Ogden, K, Pares, D, Pearce, R, Pilkington, S, Praveen, BVR, Savage, I, Scott, SM, Siddiqi, S, Smalley, L, Smart, N, Stevens, N, Stoker, C, Taylor, S, Telford, K, Tincello, D, Tinkler, L, Uddin, N, Ukoumunne, OC, Vaizey, C, Vollebregt, P, Waring, M, Webb-Wilson, H, Williams, A, Yiannakou, Y   +64 more
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Practical Recommendations of the Obesity Management Task Force of the European Association for the Study of Obesity for the Post-Bariatric Surgery Medical Management [PDF]

, 2017
Bariatric surgery is today the most effective long-term therapy for the management of patients with severe obesity, and its use is recommended by the relevant guidelines of the management of obesity in adults.
Azran, Carmil, Batterham, Rachel L, Busetto, Luca, Dicker, Dror, Farpour-Lambert, Nathalie, Fried, Martin, Hjelmes\ue6th, J\uf8ran, Kinzl, Johann, Leitner, Deborah R, Makaronidis, Janine M, Schindler, Karin, Toplak, Hermann, Yumuk, Volkan   +12 more
core   +6 more sources

Reduction of Ribonucleotide Reductase Subunit RRM2 Potentially Impairs Gut Function of Woody Breast Broilers

Animal Research and One Health, EarlyView.
Woody breast compromises meat quality leading to reduced consumer appeal. Although its causes are unclear, improvements observed with certain dietary supplements suggest that gut health may influence woody breast development. Ribonucleotide reductase subunit RRM2 is vital for mitochondrial function and gastrointestinal integrity, and alteration in its ...
Majid Shakeri, Elizabeth Ziabtchenko, Janghan Choi, Caitlin E. Harris, Richard J. Buhr, Trevor R. Mitchell, Byungwhi Kong, Hong Zhuang, Brian Bowker   +8 more
wiley   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Evaluation of the safety profile of rotavirus vaccines: a pharmacovigilance analysis on American and European data [PDF]

, 2020
Rotaviruses (RVs) are the most common cause of severe diarrheal disease. To date two rotavirus oral vaccines are licensed: Rotarix and Rotateq. Our aim was to contribute to the post-marketing evaluation of these vaccines safety profile.
Bonaldo G., Ceschi A., Motola D., Noseda R., Vaccheri A.   +4 more
core   +1 more source

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Bacterial Pneumonia in Dogs and Cats: An Update. [PDF]

, 2020
Bacterial pneumonia is a common clinical diagnosis in dogs but seems to occur less often in cats. Underlying causes include viral infection, aspiration injury, foreign body inhalation, and defects in clearance of respiratory secretions. Identification of
Dear, Jonathan D
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Early evolutionary history of the seed

Biological Reviews, EarlyView.
ABSTRACT The seed is an essential stage in the life history of gymnospermous and angiospermous plants, facilitating both their survival and dispersal. We reappraise knowledge of the evolutionary history of the gymnospermous seed, from its origin in the late Devonian through to the well‐known end‐Permian extinctions – an interval encompassing the ...
Richard M. Bateman, Alan R. T. Spencer, Jason Hilton   +2 more
wiley   +1 more source

Right hemihepatectomy for bile duct injury following laparoscopic cholecystectomy [PDF]

, 2018
Laparoscopic cholecystectomy (LC) has become the treatment of choice for patients with symptomatic cholecystolithiasis. But with the introduction of this technique, the incidence of bile duct injuries has increased.
Fellbaum, C., Heinrich, S., Krähenbühl, L., Lorenz, M., Seifert, H.   +4 more
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