Results 141 to 150 of about 4,377,369 (241)

The Conditions in Which Modularity Truly Bears Fruit: Moderation and Mediation Analyses

Creativity and Innovation Management, EarlyView.
ABSTRACT Despite modularity's prominence in contemporary innovation strategies, empirical evidence on its effectiveness remains mixed. This study addresses the inconsistent evidence on modularity's performance impact by examining its moderation and mediation effects.
Nukhet Harmancioglu, İsmail Erzurumlu, Maria Sääksjärvi   +2 more
wiley   +1 more source

sj-pdf-1-inv-10.1177_15569845241232685 – Supplemental material for Proof of Concept: Development of a Mitral Annuloplasty Ring With Crosshatch Net

Supplemental material, sj-pdf-1-inv-10.1177_15569845241232685 for Proof of Concept: Development of a Mitral Annuloplasty Ring With Crosshatch Net by Benjamin D. Seadler, David L.
Paul J. Pearson (10190415), Y. William Yuan (18138473), Kevin Sweeney (568715), David L. Joyce (6980570), James Zelten (12856986), Zoey Slettehaugh (18138470), Benjamin D. Seadler (18138464), Brandon Tefft (4254295), Taylor Wisgerhof (18138467)   +8 more
core   +1 more source

Quizartinib Resistance Mutations and Treatment Outcomes in Relapsed or Refractory FLT3‐ITD–Positive AML

Cancer Science, EarlyView.
ABSTRACT Quizartinib is a FMS‐like tyrosine kinase 3 (FLT3) inhibitor indicated for FLT3 internal tandem duplication (FLT3‐ITD)–positive acute myeloid leukemia (AML). We aimed to evaluate quizartinib resistance mechanisms, in addition to efficacy and safety outcomes, in patients with relapsed or refractory FLT3‐ITD–positive AML.
Yuichiro Semba, Toshihiro Miyamoto, Senji Kasahara, Yoshikane Kikushige, Takahiro Maeda, Goichi Yoshimoto, Shuichi Ota, Akio Saito, Yuho Najima, Hiroki Hosoi, Daigo Niiya, Koji Kato, Koji Nagafuji, Takashi Akasaka, Tomohiko Kamimura, Atsushi Takita, Maiko Narahara, Tadashi Toki, Koichi Iwanaga, Koji Yonemoto, Mine Harada, Koichi Akashi   +21 more
wiley   +1 more source

Chromosomal abnormalities in secondary MDS and AML. Relationship to drugs and radiation with specific emphasis on the balanced rearrangements

Haematologica, 1998
BACKGROUND AND OBJECTIVE: In therapy-related myelodysplasia (t-MDS) or acute myeloid leukemia (t-AML) balanced chromosome aberrations to bands 11q23 and 21q22 have been significantly related to previous chemotherapy with DNA topoisomerase II inhibitors ...
MK Andersen, B Johansson, SO Larsen, J Pedersen-Bjergaard   +3 more
doaj  

sj-pdf-1-inv-10.1177_15569845241231989 – Supplemental material for The Perceval Sutureless Bioprosthetic Aortic Valve: Evolution of Surgical Valve Technology

Supplemental material, sj-pdf-1-inv-10.1177_15569845241231989 for The Perceval Sutureless Bioprosthetic Aortic Valve: Evolution of Surgical Valve Technology by Nicholas M. Fialka, Ryaan EL-Andari, Shaohua Wang, Aleksander Dokollari, William D. T.
Ali Fatehi Hassanabad (9394362), Aleksander Dokollari (11074020), Ryaan EL-Andari (13809467), Nicholas M. Fialka (13809470), Shaohua Wang (1447912), William D. T. Kent (9394371)   +5 more
core   +1 more source

ResEdit: Residual embeddings for precise generative image editing

Computer Graphics Forum, EarlyView.
Abstract Conditional diffusion image generators can be repurposed for editing through inversion, without the need for large‐scale paired fine‐tuning data. However, producing high‐quality, targeted edits while maintaining image identity and global consistency remains challenging, as weakly conditioned inversion often embeds conflicting image features ...
Canberk Baykal, Valentin Deschaintre, Yannick Hold‐Geoffroy, Michael Fischer, Anna Frühstück, Cengiz Öztireli, Iliyan Georgiev   +6 more
wiley   +1 more source

Small lesion, big challenge? Diagnosis of small diameter melanocytic lesions by dermatologists using AI support

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Dermoscopy enhances melanoma detection, but small‐diameter melanomas (SDMs) remain diagnostically challenging. Convolutional neural networks (CNNs) may detect subtle patterns beyond human perception. This study evaluates how lesion diameter influences the diagnostic accuracy of dermatologists, with and without CNN support.
Anastasia Sophie Vollmer, Gianluca Nazzaro, Julia Katharina Winkler, Giuseppe Argenziano, Aimilios Lallas, Katharina Susanne Kommoss, Andreas Blum, Wilhelm Stolz, Carlo Maronese, Serena Giacalone, Cristina B Spigariolo, Gabriele Roccuzzo, Gianluca Avallone, Stefania Guida, Gabriella Brancaccio, Paolo Broganelli, Giovanni Pellacani, Francesca Farnetani, Emanuela Passoni, Angelo V Marzano, Alexander Enk, Holger Andreas Haenssle   +21 more
wiley   +1 more source

The Inv(16) Oncogene CBFB::MYH11 is Required for the Survival of Leukemia Cells in the Blood and Spleen, but not the Bone Marrow. [PDF]

Oncogene
Panda S, Wang Y, Dogiparthi VR, Becker M, Dhir A, Lam C, Rivas C, Alemu L, Garrett L, Xiao P, Swenson SA, Hewitt KJ, Hyde RK.   +12 more
europepmc   +1 more source

RUNX1 and inv(16) are frenemies in AML.

Blood, 2020
Rao S.
europepmc   +1 more source

Exploring the Challenges and Legal Implications of Secondary Use of Health Data in South Africa

Developing World Bioethics, EarlyView.
ABSTRACT The sharing of health data advances knowledge, fosters innovation, and promotes evidence‐based decision‐making. This practice involves using existing data for collaborative research or for purposes other than those for which it was originally collected.
Aliki Edgcumbe, Adéle Strydom, Donrich Willem Thaldar, Michael Sean Pepper   +3 more
wiley   +1 more source