Results 51 to 60 of about 75,910 (275)

Downregulation of FGF Signaling by Spry4 Overexpression Leads to Shape Impairment, Enamel Irregularities, and Delayed Signaling Center Formation in the Mouse Molar. [PDF]

, 2019
FGF signaling plays a critical role in tooth development, and mutations in modulators of this pathway produce a number of striking phenotypes. However, many aspects of the role of the FGF pathway in regulating the morphological features and the mineral ...
Ahn, Youngwook, Charles, Cyril, Ganss, Bernhard, Jheon, Andrew, Klein, Ophir D, Krumlauf, Robb, Marangoni, Pauline, Seidel, Kerstin, Viriot, Laurent   +8 more
core   +1 more source

“Nature Abhors a Vaccuum”: Invagination of the Small Intestine into the Lumbar Disc Space After a Spinal Fusion Operation

Diagnostics, 2020
A 77-year-old woman having back pain due to an L2 vertebral body compression fracture took a lumbar spine magnetic resonance imaging (MRI). In MRI, in addition to the L2 vertebral body fracture, invagination of the small intestine into the intervertebral
Wonho Lee, Mathieu Boudier-Revéret, Du Hwan Kim, Min Cheol Chang   +3 more
doaj   +1 more source

Spatial regulation of contractility by Neuralized and Bearded during furrow invagination in Drosophila

Nature Communications, 2017
Embryo-scale morphogenesis arises from patterned mechanical forces. During Drosophila gastrulation, actomyosin contractility drives apical constriction in ventral cells, leading to furrow formation and mesoderm invagination.
Gantas Perez-Mockus, Khalil Mazouni, Vanessa Roca, Giulia Corradi, Vito Conte, F. Schweisguth   +5 more
semanticscholar   +1 more source

Toward high-content/high-throughput imaging and analysis of embryonic morphogenesis [PDF]

, 2011
In vivo study of embryonic morphogenesis tremendously benefits from recent advances in live microscopy and computational analyses. Quantitative and automated investigation of morphogenetic processes opens the field to high-content and high-throughput ...
Supatto, Willy, Truong, Thai V.
core   +4 more sources

Deciphering caveolar functions by syndapin III KO-mediated impairment of caveolar invagination

eLife, 2017
Several human diseases are associated with a lack of caveolae. Yet, the functions of caveolae and the molecular mechanisms critical for shaping them still are debated.
Eric Seemann, Minxuan Sun, Sarah Krueger, Jessica Tröger, Wenya Hou, Natja Haag, Susann Schüler, M. Westermann, Christian A Huebner, B. Romeike, M. Kessels, B. Qualmann   +11 more
semanticscholar   +1 more source

Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery. [PDF]

, 2017
Neurite initiation is the first step in neuronal development and occurs spontaneously in soft tissue environments. Although the mechanisms regulating the morphology of migratory cells on rigid substrates in cell culture are widely known, how soft ...
Chang, Ting-Ya, Chang, Ya-Chu, Chen, Chen, Cheng, Pei-Lin, Guo, Chin-Lin, Lee, Min, Lu, Chi-Huan, Lu, Shao-Tzu, Wang, Aijun, Wang, De-Yao   +9 more
core   +2 more sources

PAR-dependent and geometry-dependent mechanisms of spindle positioning. [PDF]

, 2003
During intrinsically asymmetric division, the spindle is oriented onto a polarized axis specified by a group of conserved PAR proteins. Extrinsic geometric asymmetry generated by cell shape also affects spindle orientation in some systems, but how ...
Hayashi, Adam, Ku, Wei, Rose, Lesilee S, Tsou, Meng-Fu Bryan   +3 more
core  

Mechanical Stress Inference for Two Dimensional Cell Arrays [PDF]

, 2011
Many morphogenetic processes involve mechanical rearrangement of epithelial tissues that is driven by precisely regulated cytoskeletal forces and cell adhesion.
A Puliafito, AC Martin, AC Martin, AJ Engler, BI Shraiman, Boris I. Shraiman, C Bertet, D Choquet, D Weaire, DP Kiehart, E Evans, F Graner, F Meng, GW Brodland, J Folkman, J Käfer, J Stavans, JT Blankenship, Kevin K. Chiou, L He, L Hufnagel, L Wolpert, Lars Hufnagel, M Affolter, M Dembo, M Köppen, M Rauzi, M Wyart, MA Wozniak, O Hamant, R Farhadifar, R Goodyear, RA Foty, S Bao, S Gilbert, S Huang, S Huang, SJ Bray, SL Campbell, SM Hutson, Stanislav Shvartsman, T Hayashi, T Lecuit, V Mirabet   +43 more
core   +5 more sources

Two-step regulation of trachealess ensures tight coupling of cell fate with morphogenesis in the Drosophila trachea

eLife, 2019
During organogenesis, inductive signals cause cell differentiation and morphogenesis. However, how these phenomena are coordinated to form functional organs is poorly understood.
Takefumi Kondo, Shigeo Hayashi
doaj   +1 more source

Patterning of the C. elegans 1° vulval lineage by RAS and Wnt pathways [PDF]

, 2000
In C. elegans, the descendants of the 1° vulval precursor cell (VPC) establish a fixed spatial pattern of two different cell fates: E-F-F-E. The two inner granddaughters attach to the somatic gonadal anchor cell (AC) and generate four vulF cells, while ...
Sternberg, Paul W., Wang, Minqin
core