Results 91 to 100 of about 2,722,864 (238)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
On Sullivan’s invariant measure problem
, 1988 Sullivan has posed an invariant measure problem for which a positive answer is very plausible. It also seems highly plausible that hyperfinite AW*-factors are injective. Surprisingly, it turns out that one of these problems must have a negative solution.
L. J. Bunce, J. D. Maitland Wright
core +1 more source
Density Formula in Malliavin Calculus by Using Stein’s Method and Diffusions
MathematicsLet G be a random variable of functionals of an isonormal Gaussian process X defined on some probability space. Studies have been conducted to determine the exact form of the density function of the random variable G.
Hyun-Suk Park
doaj +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
, 2015 We provide an example of a discrete-time Markov process on the three-dimensional infinite integer lattice with Zq-invariant Bernoulli-increments which has as local state space the cyclic group Zq.
Külske, Christof +3 more
core +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Ergodicity of the two-dimensional magnetic Benard problem
Electronic Journal of Differential Equations, 2016 We study the two-dimensional magnetic Benard problem with noise, white in time. We prove the well-posedness including the path-wise uniqueness of the generalized solution, and the existence of the unique invariant, and consequently ergodic, measure ...
Kazuo Yamazaki
doaj
Higher d Eisenstein series and a duality-invariant distance measure
Journal of High Energy PhysicsThe Petersson inner product is a natural inner product on the space of modular invariant functions. We derive a formula, written as a convergent sum over elementary functions, for the inner product E s (G, B) of the real analytic Eisenstein series $${E}_{
Nathan Benjamin, A. Liam Fitzpatrick
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source