Results 91 to 100 of about 716,820 (275)

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Measures of concordance determined by D4-invariant copulas

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2004
A continuous random vector (X,Y) uniquely determines a copula C:[0,1]2→[0,1] such that when the distribution functions of X and Y are properly composed into C, the joint distribution function of (X,Y) results.
H. H. Edwards   +2 more
doaj   +1 more source

Metric Structure of the Space of Two-Qubit Gates, Perfect Entanglers and Quantum Control

open access: yesEntropy, 2013
We derive expressions for the invariant length element and measure for the simple compact Lie group SU(4) in a coordinate system particularly suitable for treating entanglement in quantum information processing.
Paul Watts   +2 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

On Relatively Invariant Measures [PDF]

open access: yesCanadian Journal of Mathematics, 1960
In this note we will discuss the question of the measurability of the multiplier function of a relatively invariant measure on a group. That is, for a group G, σ-ring S, and a measure μ defined on the sets of S, we assume: E in S, x in G implies xE is in S and μ(XE) = σ(x)μ(E) and study the measurability of the function σ(x).The problem was discussed ...
openaire   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

𝒞m-smoothness of invariant fiber bundles for dynamic equations on measure chains

open access: yesAdvances in Difference Equations, 2004
We present a new self-contained and rigorous proof of the smoothness of invariant fiber bundles for dynamic equations on measure chains or time scales.
Stefan Siegmund   +1 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

With Andrzej Lasota There and Back Again

open access: yesAnnales Mathematicae Silesianae
The paper below is a written version of the 17th Andrzej Lasota Lecture presented on January 12th, 2024 in Katowice. During the lecture we tried to show the impact of Andrzej Lasota’s results on the author’s research concerning various fields of ...
Rudnicki Ryszard
doaj   +1 more source

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